M0398

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone

elastase inhibitor, powder, ≥98% (TLC)

• 同義詞: N-(Methoxysuccinyl)-L-alanyl-L-alanyl-L-prolyl-L-valine chloromethylketone
• 經驗公式（希爾表示法）: C₂₂H₃₅ClN₄O₇
• CAS號碼: 65144-34-5
• 分子量：: 502.99
• Beilstein: 6167019
• MDL號碼: MFCD00077136
• 分類程式碼代碼: 12352202
• PubChem物質ID: 24896552
• NACRES: NA.77

屬性

• 產品名稱: N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone, elastase inhibitor
• 品質等級: 200
• 化驗: ≥98% (TLC)
• 形狀: powder
• mp: 159 °C
• 溶解度: methanol: 50 mg/mL, clear, colorless
• 儲存溫度: −20°C
• SMILES 字串: COC(=O)CCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)CCl
• InChI: 1S/C22H35ClN4O7/c1-12(2)19(16(28)11-23)26-21(32)15-7-6-10-27(15)22(33)14(4)25-20(31)13(3)24-17(29)8-9-18(30)34-5/h12-15,19H,6-11H2,1-5H3,(H,24,29)(H,25,31)(H,26,32)/t13-,14-,15-,19-/m0/s1
• InChI 密鑰: PJGDFLJMBAYGGC-XLPNERPQSA-N

描述

一般說明

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is a tetrapeptide, cell-permeable and non-cytotoxic inhibitor.

應用

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone has been used as an elastase specific inhibitor.

生化／生理作用

N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone acts as a competitive inhibitor of human leukocyte elastase (HLE).

Irreversible inhibitor of human leukocyte and neutrophil elastase.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)