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Merck
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重要文件

L7770

Sigma-Aldrich

脂多糖 来源于肠沙门氏菌 肠炎血清型

γ-irradiated, BioXtra, suitable for cell culture

同義詞:

LPS

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About This Item

MDL號碼:
分類程式碼代碼:
12352201
NACRES:
NA.75

生物源

Salmonella enterica (Serotype enteritidis)

品質等級

無菌

γ-irradiated

產品線

BioXtra

形狀

lyophilized powder

純化經由

gel-filtration chromatography

技術

cell culture | mammalian: suitable

雜質

<1% Protein (Lowry)

顏色

white to yellow cast

溶解度

water: 4.90-5.10 mg/mL, faintly hazy to hazy, colorless

儲存溫度

2-8°C

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應用

来自血清型肠炎沙门氏菌的脂多糖可用于细胞培养和细胞结合应用。它被用于研究炎症在神经病理性疼痛和动脉瘤进展中的作用
脂多糖 (LPS) 是革兰氏阴性菌细胞壁的特征性成分。LPS 及其脂质 A 部分通过 Toll 样受体 4 (TLR4) 刺激天然免疫系统的细胞。

生化/生理作用

脂多糖(LPS)是革兰氏阴性细菌细胞壁的特征组分。LPS及其脂质A部分可通过Toll样受体4(TLR4)刺激细胞的先天免疫系统,Toll样受体4是Toll样受体蛋白家族的成员,其可识别常见的病原体相关分子模式(PAMP)。

其他說明

为了全面了解我们针对客户研究提供的各种脂多糖产品,建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Rosemary Fernandez et al.
Bio-protocol, 5(11) (2016-07-23)
Phosphorylation of tyrosine, serine, and threonine residues is critical for the control of protein activity involved in various cellular events. An assortment of kinases and phosphatases regulate intracellular protein phosphorylation in many different cell signaling pathways. These pathways include T
Ryan Gene Soderquist et al.
Pharmaceutical research, 27(5), 841-854 (2010-03-13)
Interleukin-10 (IL-10) is an anti-inflammatory molecule that has achieved interest as a therapeutic for neuropathic pain. In this work, the potential of plasmid DNA-encoding IL-10 (pDNA-IL-10) slowly released from biodegradable microparticles to provide long-term pain relief in an animal model
Anita Mikołajczyk et al.
Gut pathogens, 9, 73-73 (2017-12-20)
The present research was conducted to investigate the influence of a low, single dose of LPS, which does not result in any clinical symptoms of intoxication on the expression of selected neuropeptides within the intestines of the domestic pig. This
Christopher J Neufeldt et al.
PLoS pathogens, 9(10), e1003744-e1003744 (2013-11-10)
Hepatitis C virus (HCV) infection induces formation of a membranous web structure in the host cell cytoplasm where the viral genome replicates and virions assemble. The membranous web is thought to concentrate viral components and hide viral RNA from pattern
Anita Mikołajczyk et al.
Toxins, 11(2) (2019-02-06)
Bacterial lipopolysaccharide (LPS) can contribute to the pathogenesis and the clinical symptoms of many diseases such as cancer, mental disorders, neurodegenerative as well as metabolic diseases. The asymptomatic carrier state of Salmonella spp. is a very important public health problem.

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