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About This Item
經驗公式（希爾表示法）:
C12H9F3N2O2
CAS號碼:
分子量：:
270.21
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77
推薦產品
品質等級
化驗
≥98% (TLC)
形狀
powder
mp
166.5 °C
溶解度
methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow
作用方式
enzyme | inhibits
儲存溫度
2-8°C
SMILES 字串
Cc1oncc1C(=O)Nc2ccc(cc2)C(F)(F)F
InChI
1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18)
InChI 密鑰
VHOGYURTWQBHIL-UHFFFAOYSA-N
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應用
由于其免疫抑制作用，来氟米特被发现可用于器官移植 、类风湿关节炎 和其他自身免疫性疾病的治疗。
生化／生理作用
免疫抑制；抑制 T、B 细胞增殖。活性主要归因于其代谢产物丙二腈衍生物，后者被认为抑制二氢乳清酸脱氢酶（在 新生 嘧啶合成途径中）以及几种蛋白酪氨酸激酶。
訊號詞
Danger
危險分類
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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