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Merck
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重要文件

L4754

Sigma-Aldrich

3-sn-溶血磷脂酰乙醇胺 来源于鸡蛋黄

Type I, ≥99%

同義詞:

1-酰基-sn-甘油-3-磷(2-氨基乙醇), L-α-溶血磷脂酰乙醇胺

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About This Item

MDL號碼:
分類程式碼代碼:
51191904
NACRES:
NA.25

生物源

egg yolk

品質等級

種類

Type I

化驗

≥99%

形狀

powder

脂質類型

phosphoglycerides

運輸包裝

ambient

儲存溫度

−20°C

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一般說明

溶血磷脂酰乙醇胺(LysoPE)是溶血磷脂的重要组成部分,由磷脂酰乙醇胺部分水解得到。

應用

鸡蛋黄来源的3-sn-溶血磷脂酰乙醇胺已用于:
  • 制备脂用于脂质体结合和囊泡测定的质体
  • 用作高效薄层色谱 (HPTLC) 中的磷脂标准品,检测血小板来源微粒的磷脂组成
  • 用作薄层色谱(TLC)中的磷脂标准品,鉴定含有利什曼原虫的带虫空泡(PV) 中的磷脂

生化/生理作用

溶血磷脂酰乙醇胺(LPE)参与神经系统的生理和病理进程。它在细胞膜功能、细胞凋亡、氧化压力和炎症反应中具有关键作用。
蛋黄中的L-α-溶血磷脂酰乙醇胺富含硬脂酸和棕榈酸酰化脂肪酸。

品質

主要含有硬脂酸和棕榈酸。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Nguyen Dang Hung et al.
Lipids, 46(10), 893-906 (2011-07-12)
In the present study, the anti-inflammatory action of lysophosphatidylethanolamine (lysoPtdEtn), orally administered, in zymosan A-induced peritonitis was examined. Oral administration of 2-DHA-lysoPtdEtn (ED(50), ~111 μg/kg) or 2-ARA-lysoPtdEtn (ED(50), 221 μg/kg) was found to inhibit the plasma leakage in mice treated with zymosan
Yuan-Yuan Zhao et al.
Journal of chromatography. A, 1218(32), 5470-5479 (2011-07-09)
A hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC LC-MS/MS) method using multiple scan modes was developed to separate and quantify 11 compounds and lipid classes including acetylcholine (AcCho), betaine (Bet), choline (Cho), glycerophosphocholine (GPC), lysophosphatidylcholine (LPC), lysophosphatidylethanolamine (LPE), phosphatidylcholine (PC)
Madhavi Avadhani et al.
Journal of bacteriology, 188(24), 8543-8550 (2006-10-10)
Short-chain alcohol dehydrogenases (SCADHs) synthesize a variety of intercellular signals and other chemically diverse products. It is difficult to predict the substrate of a SCADH on the basis of amino acid sequence homology, as the substrates are not known for
E Biró et al.
Journal of thrombosis and haemostasis : JTH, 3(12), 2754-2763 (2005-12-20)
The processes that govern the distribution of molecules between platelets and the microparticles (MP) they release are unknown. Certain proteins are sorted selectively into MP, but lipid sorting has not been studied. To compare the phospholipid composition and cholesterol content
Kumiko Makide et al.
Prostaglandins & other lipid mediators, 89(3-4), 135-139 (2009-05-12)
It is now widely accepted that lysophospholipids (LPLs), a product of the phospholipase A reaction, function as mediators through G-protein-coupled receptors. Notably, recent studies of lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) have revealed their essential roles in vivo. On

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