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846725C

Avanti

18:1 Lyso PE

1-oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine, chloroform

同義詞:

1--(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; PE(18:1(9Z)/0:0)

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About This Item

經驗公式（希爾表示法）:
C23H46NO7P
CAS號碼:
89576-29-4
分子量：:
479.59
分類程式碼代碼:
51191904
NACRES:
NA.25

化驗

>99% (LPE; may contain up to 10% of the 2-LPE isomer, TLC)

形狀

liquid

包裝

pkg of 1 × 2.5 mL (846725C-25mg)
pkg of 2 × 20 mL (846725C-1g)
pkg of 2 × 4 mL (846725C-200mg)

製造商／商標名

Avanti Research™ - A Croda Brand 846725C

濃度

10 mg/mL (846725C-25mg)
25 mg/mL (846725C-1g)
25 mg/mL (846725C-200mg)

脂質類型

phospholipids
cardiolipins

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

O[C@](COP([O-])(OCC[NH3+])=O)([H])COC(CCCCCCC/C=C\CCCCCCCC)=O

相關類別

一般說明

Lyso-phosphatidylethanolamine (lysoPE) is a structural isomer which carries an oleic acid at the sn-1 position. This lipid occurs naturally.

應用

18:1 Lyso PE (1-oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine) has been used as a lipid standard in the optimization of the liquid chromatography−mass spectrometry (LC-MS) method conditions. It may be used to study its effects on [Ca2+]i in PC-12 neuronal cells, MDA-MB-231 and SK-OV3 cells.

生化／生理作用

Lyso-phosphatidylethanolamine (lysoPE) can serve as a substrate for SocA, the short-chain alcohol dehydrogenase. It helps to delay the senescence in the plant parts.

包裝

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (846725C-1g)
5 mL Clear Glass Sealed Ampule (846725C-200mg)
5 mL Clear Glass Sealed Ampule (846725C-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard
GHS06,GHS08

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

標靶器官

Liver,Kidney, Respiratory system

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

does not flash

閃點（°C）

does not flash

分析證明 (COA)

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Soo-Jin Park et al.
Biomolecules & therapeutics, 22(2), 129-135 (2014-04-23)
Previously, we reported that lysophosphatidylethanolamine (LPE), a lyso-type metabolite of phosphatidylethanolamine, can increase intracellular Ca(2+) ([Ca(2+)]i) via type 1 lysophosphatidic acid (LPA) receptor (LPA1) and CD97, an adhesion G-protein-coupled receptor (GPCR), in MDA-MB-231 breast cancer cells. Furthermore, LPE signaling was
Kelly M Hines et al.
Chemistry and physics of lipids, 219, 15-22 (2019-01-21)
Our understanding of phospholipid biosynthesis in Gram-positive and Gram-negative bacteria is derived from the prototypical Gram-negative organism Escherichia coli. The inner and outer membranes of E. coli are largely composed of phosphatidylethanolamine (PE), minor amounts of phosphatidylglycerol (PG) and cardiolipin
Madhavi Avadhani et al.
Journal of bacteriology, 188(24), 8543-8550 (2006-10-10)
Short-chain alcohol dehydrogenases (SCADHs) synthesize a variety of intercellular signals and other chemically diverse products. It is difficult to predict the substrate of a SCADH on the basis of amino acid sequence homology, as the substrates are not known for
Svenja Bockelmann et al.
Journal of lipid research, 59(3), 515-530 (2018-01-19)
Ceramides are central intermediates of sphingolipid metabolism with dual roles as mediators of cellular stress signaling and mitochondrial apoptosis. How ceramides exert their cytotoxic effects is unclear and their poor solubility in water hampers a search for specific protein interaction
Mónica Narváez-Rivas et al.
Journal of chromatography. A, 1440, 123-134 (2016-03-02)
The goal of untargeted lipidomics is to have high throughput, yet comprehensive and unambiguous identification and quantification of lipids. Novel stationary phases in LC separation and new mass spectrometric instruments capable of high mass resolving power and faster scanning rate

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