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Key Documents

L2378

Sigma-Aldrich

γ-亚麻酸

≥99%, liquid

同義詞:

γ-亚麻酸, 顺,顺,顺-6,9,12-十八碳三烯酸

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About This Item

經驗公式(希爾表示法):
C18H30O2
CAS號碼:
分子量::
278.43
Beilstein:
1712253
MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.25

生物源

plant oil (borage)

化驗

≥99%

形狀

liquid

官能基

carboxylic acid

脂質類型

omega FAs

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

CCCCC\C=C/C\C=C/C\C=C/CCCCC(O)=O

InChI

1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10,12-13H,2-5,8,11,14-17H2,1H3,(H,19,20)/b7-6-,10-9-,13-12-

InChI 密鑰

VZCCETWTMQHEPK-QNEBEIHSSA-N

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應用

γ-亚麻酸已被用作气相色谱法的分析标准品。 可用于有关体重增加的营养研究和可能的肿瘤抑制药物。γ-亚麻酸用于研究不饱和脂肪酸的氧化/过氧化机制和预防。

生化/生理作用

γ-亚麻酸盐 (C18:6,9,12) 与 α -亚麻酸 (C18:9,12,15) 在双键不同的位置。
γ-亚麻酸,一种多不饱和脂肪酸,通过降低人肠细胞样细胞系 Caco-2 和人中白细胞介素 (IL) 6 和 IL-8 的以及人体外树突状细胞产量发挥抗炎效果

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

230.0 °F - closed cup

閃點(°C)

110 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


分析證明 (COA)

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存取文件庫

Julianne Lindemann et al.
Current medical research and opinion, 25(12), 2865-2875 (2009-10-09)
Asthma can have a negative impact on quality of life although this is not well correlated with objective evaluations of pulmonary function. A medical food, EFF1009, containing the fatty acids gamma-linolenic acid (GLA) and eicosapentaenoic acid (EPA) decreases leukotriene B(4)
J Hindo et al.
Radiation research, 153(2), 201-207 (2000-01-12)
Peroxidation of unconjugated polyunsaturated fatty acids such as linolenic acid proceeds through a free radical chain mechanism and is accompanied by the formation of conjugated dienes such as hydroperoxides. In an investigation of radiation-induced oxidation of aqueous linolenate, we have
V A Ziboh et al.
The American journal of clinical nutrition, 71(1 Suppl), 361S-366S (2000-01-05)
In the skin epidermis, the metabolism of polyunsaturated fatty acids (PUFAs) is highly active. Dietary deficiency of linoleic acid (LA), the major 18-carbon n-6 PUFA in normal epidermis, results in a characteristic scaly skin disorder and excessive epidermal water loss.
P Darcet et al.
Annales de la nutrition et de l'alimentation, 34(2), 277-290 (1980-01-01)
33 healthy men, 72 years old on average, ingested during five week: 2,4 g of Oenothera Biennis oil rich in PUFA. Before and after ingestion, platelet aggregation was measured according to the Born's photometric method, which divided the original group
Inmaculada Tasset-Cuevas et al.
PloS one, 8(2), e56986-e56986 (2013-03-06)
Borage (Borago officinalis L.) seed oil has been used as a treatment for various degenerative diseases. Many useful properties of this oil are attributed to its high gamma linolenic acid content (GLA, 18:3 ω-6). The purpose of this study was

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