L020000

TCA 脱保护剂

• 分類程式碼代碼: 41116105
• NACRES: NA.21

屬性

• 種類: for DNA synthesis, for DNA synthesis; for DNA synthesis
• 儲存條件: dry at room temperature
• 濃度: 28-32 g/L (TCA content, titration)
• 雜質: ≤200 ppm water content (Karl Fischer)
• 顏色: clear; clear

描述

準備報告

三氯乙酸/二氯甲烷 3/100（v/v）

其他說明

Deblock solution containing trichloroacetic acid (TCA) in dichloromethane removes the dimethoxytrityl (DMT) protecting group from the 5′hydroxyl moiety of nucleotides already incorporated into the growing nucleic acid, prior to the addition of the next phosphoramidite. Removal of the DMT allows the unprotected 5′hydroxyl moiety to react with a new phosphoramidite in a subsequent extension reaction.

安全資訊

• 象形圖: GHS08,GHS05,GHS07,GHS09
• 訊號詞: Danger
• 危險聲明: H315,H318,H335,H336,H351,H411
• 防範說明: P202 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• 危險分類: Aquatic Chronic 2 - Carc. 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Central nervous system, Respiratory system
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 212.0 °F - closed cup
• 閃點（°C）: 100 °C - closed cup