JN0004

Tolmetin sodium dihydrate

≥98% (HPLC)

• 同義詞: Tolmetin sodium salt dihydrate, 1-Methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic acid sodium salt dihydrate, Sodium 2-(1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl)acetate dihydrate, 1-Methyl-5-(p-toluoyl)pyrrole-2-acetic acid sodium salt dihydrate
• 線性公式: C₁₅H₁₄NO₃Na · 2H₂O
• CAS號碼: 64490-92-2
• 分子量：: 315.30
• MDL號碼: MFCD00150761
• 分類程式碼代碼: 12352200
• NACRES: NA.77

屬性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: H₂O: 2 mg/mL, clear
• 儲存溫度: room temp
• SMILES 字串: [Na+].[H]O[H].[H]O[H].Cc1ccc(cc1)C(=O)c2ccc(CC([O-])=O)n2C
• InChI: 1S/C15H15NO3.Na.2H2O/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18;;;/h3-8H,9H2,1-2H3,(H,17,18);;2*1H2/q;+1;;/p-1
• InChI 密鑰: QQILXENAYPUNEA-UHFFFAOYSA-M
• 基因資訊: human ... PTGS1(5742) , PTGS2(5743)

描述

生化／生理作用

Tolmetin sodium is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin synthetase in vitro and reduces plasma levels of prostaglandin E. Tolmetin sodium exhibits anti-inflammatory, analgesic and antipyretic activity Its precise mechanism of is unknown. Tolmetin is used to treat rheumatoid arthritis, osteoarthrosis, pain, and ankylosing spondylitis.

安全資訊

• 象形圖: GHS08,GHS07
• 訊號詞: Warning
• 危險聲明: H302,H361d
• 防範說明: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• 危險分類: Acute Tox. 4 Oral - Repr. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable