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I6256

Sigma-Aldrich

2-亚氨基硫烷 盐酸盐

≥98% (TLC), powder

同義詞:

2-亚氨基硫杂环戊烷 盐酸盐, 2-亚氨基硫烷盐酸盐 盐酸盐, 2IT, Traut 试剂

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About This Item

經驗公式（希爾表示法）:
C4H7NS · HCl
CAS號碼:
4781-83-3
分子量：:
137.63
Beilstein:
3620079
MDL號碼:
MFCD00039013
分類程式碼代碼:
12352100
PubChem物質ID:
24896086
NACRES:
NA.21

等級

for analytical purposes

化驗

≥98% (TLC)

形狀

powder

雜質

≤5% Free sulfhydryl groups

mp

198-201 °C (lit.)

溶解度

H2O: 100 mg/mL

官能基

thioether

儲存溫度

2-8°C

SMILES 字串

N=C1SCCC1.Cl

InChI

1S/C4H7NS.ClH/c5-4-2-1-3-6-4;/h5H,1-3H2;1H

InChI 密鑰

ATGUDZODTABURZ-UHFFFAOYSA-N

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一般說明

2-氨基硫代乙烷盐酸盐（2-IT.HCl），一种蛋白质修饰试剂，通常用于将硫醇基团连接到蛋白质和肽上。用 2-IT 修饰的毛发角蛋白纤维的拉曼光谱分析。HCl 显示出新的二硫化物基团的形成。

應用

2-硫代乙烯基盐酸盐已用于合成硫醇化 PEG（聚（乙二醇））。它可用于合成 PLA-SH（聚乙二醇-硫醇）和 PLA-PEG-SH（聚乙二醇-聚乳酸-硫醇）。
伯胺的硫醇化试剂。在 pH 7-10 下，通过脒键反应，得到游离巯基。 可用于制备二硫化物和/或硫醚连接的缀合物。

其他說明

注意：脒键具有初始伯胺的正电荷。包含五个原子的连接臂。

象形圖

Skull and crossbones
GHS06

訊號詞

Danger

危險聲明

H301

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
SLCL4349
SLCK8610
SLCK5080
SLCK4538
SLCJ8672

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Akio Kuzuhara
Biopolymers, 79(4), 173-184 (2005-09-08)
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R R Traut et al.
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International journal of molecular sciences, 19(3) (2018-03-03)
We recently have established a successful xenograft model of human glioblastoma cells by enriching hyaluronic acid-dependent spheroid-forming populations termed U251MG-P1 cells from U251MG cells. Since U251MG-P1 cells have been confirmed to express CD44 along with principal stemness marker genes, OCT3/4
Alexander Ewe et al.
Nanomedicine : nanotechnology, biology, and medicine, 13(1), 209-218 (2016-08-25)
Therapeutic applications of RNA interference (RNAi) require efficient siRNA delivery strategies in vivo. Combining lipid-based carriers with polymeric nanoparticles offers the favorable properties of both systems. This is the first study to explore polyethylenimine-based lipopolyplexes comprising a low-molecular weight PEI
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