I1637

Ipratropium bromide monohydrate

≥98% (TLC), powder

• 同義詞: Atropine isopropyl bromide
• 經驗公式（希爾表示法）: C₂₀H₃₀BrNO₃ · H₂O
• CAS號碼: 66985-17-9
• 分子量：: 430.38
• EC號碼: 244-873-8
• MDL號碼: MFCD00792907
• 分類程式碼代碼: 12352200
• PubChem物質ID: 24277843
• NACRES: NA.77

屬性

• 品質等級: 200
• 化驗: ≥98% (TLC)
• 形狀: powder
• 顏色: white
• 溶解度: H₂O: 10 mg/mL
• 起源: Boehringer Ingelheim
• SMILES 字串: O.[Br-].CC(C)[N@+]1(C)[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3
• InChI: 1S/C20H30NO3.BrH.H2O/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15;;/h4-8,14,16-19,22H,9-13H2,1-3H3;1H;1H2/q+1;;/p-1/t16-,17+,18+,19?,21?;;
• InChI 密鑰: KEWHKYJURDBRMN-XSAPEOHZSA-M
• 基因資訊: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131) , CHRM4(1132) , CHRM5(1133)

描述

應用

Ipratropium bromide monohydrate has been used for the inhibition of peripheral muscarinic receptors in rats.

生化／生理作用

Ipratropium bromide monohydrate is a nonselective muscarinic acetylcholine receptor antagonist and a bronchodilator. In nebulized form, it is used for treating asthma and obstructive pulmonary diseases. It acts as a β₂ adrenoreceptor agonist. Ipratropium bromide monohydrate is an anticholinergic agent and competes with acetylcholine. It promotes bronchodilation by stimulating sympathetic pathways.

特點和優勢

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

其他說明

N-isopropyl quaternary salt of atropine.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302 + H332,H319
• 防範說明: P261 - P264 - P271 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2