I1633

氧化胰岛素链 A 铵盐 来源于牛胰腺

≥80% (HPLC), powder

• 線性公式: C₉₇H₁₅₁N₂₅O₄₆S₄ · (NH₃)_x
• CAS號碼: 77282-71-4
• 分子量：: 2531.64 (free acid basis)
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• 生物源: bovine
• 無菌: non-sterile
• 化驗: ≥80% (HPLC)
• 形狀: powder
• UniProt登錄號: P01317
• 運輸包裝: ambient
• 儲存溫度: −20°C
• SMILES 字串: [S](=O)(=O)(O)C[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CN)[C@H](CC)C)C(C)C)CCC(=O)O)CCC(=O)N)C[S](=O)(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C[S](=O)(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)
• InChI: 1S/C97H151N25O46S4/c1-12-46(10)77(120-72(131)35-98)96(154)122-76(45(8)9)94(152)107-55(24-28-74(134)135)79(137)104-53(22-26-69(100)128)82(140)116-66(40-171(163,164)165)93(151)118-64(38-169(157,158)159)90(148)103-47(11)78(136)114-63(37-124)89(147)121-75(44(6)7)95(153)119-67(41-172(166,167)168)92(150)115-62(36-123)88(146)109-57(30-43(4)5)84(142)110-58(31-48-13-17-50(125)18-14-48)85(143)105-52(21-25-68(99)127)80(138)108-56(29-42(2)3)83(141)106-54(23-27-73(132)133)81(139)112-60(33-70(101)129)87(145)111-59(32-49-15-19-51(126)20-16-49)86(144)117-65(39-170(160,161)162)91(149)113-61(97(155)156)34-71(102)130/h13-20,42-47,52-67,75-77,123-126H,12,21-41,98H2,1-11H3,(H2,99,127)(H2,100,128)(H2,101,129)(H2,102,130)(H,103,148)(H,104,137)(H,105,143)(H,106,141)(H,107,152)(H,108,138)(H,109,146)(H,110,142)(H,111,145)(H,112,139)(H,113,149)(H,114,136)(H,115,150)(H,116,140)(H,117,144)(H,118,151)(H,119,153)(H,120,131)(H,121,147)(H,122,154)(H,132,133)(H,134,135)(H,155,156)(H,157,158,159)(H,160,161,162)(H,163,164,165)(H,166,167,168)/t46-,47-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,75-,76-,77-/m0/s1
• InChI 密鑰: WYHLQQAVJPCFKN-DQLAGKHYSA-N
• 基因資訊: cow ... INS(280829)

描述

Amino Acid Sequence

Gly-Ile-Val-Glu-Gln-Cys(SO3H)-Cys(SO3H)-Ala-Ser-Val-Cys(SO3H)-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys(SO3H)-Asn

生化／生理作用

胰岛素调节细胞对葡萄糖、氨基酸和脂肪酸的摄取、使用和储存。可抑制糖原、蛋白质和脂肪的降解。α 链含有链内二硫键。

Human insulin is made up of 51 amino acids. It consists of two peptide chains, 21 amino acids make up A-chain and chain B contains 31 amino acids. The two chains are linked together by a disulfide bond, to form a classical insulin fold with three α helices, chain A having two and one in chain B.

準備報告

制备参照 Sanger, F. 等人刊登于 Biochem. J., 44, 126 (1949) 的方法并加以改进。

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)