推薦產品
生物源
rat
品質等級
共軛
unconjugated
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
37895, monoclonal
形狀
lyophilized powder
物種活性
mouse
技術
flow cytometry: suitable
neutralization: suitable
western blot: suitable
同型
IgG2a
UniProt登錄號
儲存溫度
−20°C
基因資訊
mouse ... Ifng(15978)
一般說明
Interferon-γ (IFN-γ) belongs to Type II class of interferons and is produced by T helper cells (specifically, Th1 cells), natural killer (NK) and natural killer T (NKT) cells and cytotoxic T cells (TC cells) . It has various biological functions including antiviral activity like inhibition of cell or tumor growth, act as a potent modulator of immune responses and modifies cellular processes as well as stimulates the differentiation of B cells into immunoglobulin-producing cells. Monoclonal Anti-Interferon-γ antibody can be used in immunoblotting. Rat anti-Interferon-γ antibody has shown no cross-reactivity for recombinant human IFN-γ or recombinant rat IFN-γ.
特異性
The antibody does not cross-react with recombinat human IFN-γ or recombinant rat IFN-γ.
免疫原
recombinant mouse IFN-γ.
應用
Monoclonal Anti-Interferon-γ antibody can be used in neutralization and indirect ELISA.
外觀
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline and 5% trehalose.
準備報告
Purified from cell culture supernatant using protein G.
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儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
J Vilcek et al.
Journal of immunology (Baltimore, Md. : 1950), 135(3), 1851-1856 (1985-09-01)
Interferon (IFN)-gamma production, stimulated by the addition of exogenous interleukin (IL) 2, T cell mitogens, or tuberculin purified protein derivative (PPD) was studied in cultures of separated human mononuclear cells or unseparated peripheral blood leukocytes (PBL). IFN-gamma was induced by
P B Fisher et al.
Pharmacology & therapeutics, 27(2), 143-166 (1985-01-01)
As described in this review, both partially purified and recombinant interferons are potent modulators of differentiation in diverse cell culture systems (Table 2). Depending on the target cell, interferon exerts either an inhibitory or an inductive effect on cell differentiation.
I Gresser et al.
Proceedings of the National Academy of Sciences of the United States of America, 66(4), 1052-1058 (1970-08-01)
Mouse interferon preparations inhibited the multiplication of mouse leukemia L 1210 cells in stationary suspension cultures. The degree of inhibition was found to correlate with the antiviral titer of the interferon preparations. The factor(s) responsible for inhibition of L 1210
P D Benech et al.
The Journal of experimental medicine, 176(4), 1115-1123 (1992-10-01)
The human Fc gamma RI (CD64) is a high affinity receptor for the Fc portion of immunoglobulin (Ig), and its constitutively low expression on the cell surface of monocyte/macrophage and neutrophils is selectively upregulated by interferon gamma (IFN-gamma) treatment (Perussia
Jamie R Schoenborn et al.
Advances in immunology, 96, 41-101 (2007-11-06)
Interferon-gamma (IFN-gamma) is crucial for immunity against intracellular pathogens and for tumor control. However, aberrant IFN-gamma expression has been associated with a number of autoinflammatory and autoimmune diseases. This cytokine is produced predominantly by natural killer (NK) and natural killer
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