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About This Item
經驗公式(希爾表示法):
C4H9NO5S
CAS號碼:
分子量::
183.18
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.32
推薦產品
產品名稱
L-同型半胱氨酸, ≥95%
品質等級
化驗
≥95%
≥98% (TLC)
形狀
powder
顏色
white to off-white
應用
cell analysis
SMILES 字串
N[C@@H](CCS(O)(=O)=O)C(O)=O
InChI
1S/C4H9NO5S/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H,8,9,10)/t3-/m0/s1
InChI 密鑰
VBOQYPQEPHKASR-VKHMYHEASA-N
相關類別
應用
L-同型半胱氨酸已被用于研究在神经系统中过氧化氢介导的生理和病理状态变化。
生化/生理作用
L-同型半胱氨酸(L-HCA)是NMDA(N-甲基-D-天冬氨酸)受体的一种内源性神经递质配体。它是谷氨酸的一种类似物,可竞争性抑制神经元中谷氨酸-半胱氨酸(xc-)反转运蛋白的功能,引起半胱氨酸摄取量下降。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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L-Homocysteic acid (L-HCA) has been proposed as a natural transmitter at the N-methyl-D-aspartate (NMDA) subtype of excitatory amino acid receptor based on recent evidence that L-HCA occurs L-HCA occurs naturally in the mammalian CNS, is released from K+ stimulated brain
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Neuroscience letters, 81(1-2), 188-192 (1987-10-16)
The effects of ionophoretically applied L-homocysteate (L-HCA), L-glutamate (L-Glu) and N-methyl-D-aspartate (NMDA) were compared in rat neocortical neurons recorded intracellularly in vitro. The firing pattern and the time course of membrane depolarization induced by L-HCA resembled those of NMDA responses.
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