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Key Documents

H6886

Sigma-Aldrich

S -己基谷胱甘肽

>98% (TLC), suitable for ligand binding assays

同義詞:

还原型 S-己基-L-谷胱甘肽

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About This Item

經驗公式(希爾表示法):
C16H29N3O6S
CAS號碼:
分子量::
391.48
Beilstein:
5629635
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.26

product name

S -己基谷胱甘肽,

化驗

>98% (TLC)

形狀

powder

技術

ligand binding assay: suitable

mp

200-202 °C

儲存溫度

2-8°C

SMILES 字串

CCCCCCSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O

InChI

1S/C16H29N3O6S/c1-2-3-4-5-8-26-10-12(15(23)18-9-14(21)22)19-13(20)7-6-11(17)16(24)25/h11-12H,2-10,17H2,1H3,(H,18,23)(H,19,20)(H,21,22)(H,24,25)/t11-,12-/m0/s1

InChI 密鑰

HXJDWCWJDCOHDG-RYUDHWBXSA-N

Amino Acid Sequence

S-Hexyl-Glu-Cys-Gly

應用

用于谷胱甘肽-S-转移酶和谷胱甘肽过氧化物酶的亲和色谱法的配体。

生化/生理作用

S-己基谷胱甘肽可用作谷胱甘肽-S-转移酶和谷胱甘肽过氧化物酶的亲和色谱配体。S-己基谷胱甘肽也用作抑制剂,研究酶的特异性和动力学,如线粒体膜结合谷胱甘肽转移酶 (mtMGST1)。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Natalya Kurochkina et al.
Journal of theoretical biology, 283(1), 92-102 (2011-05-31)
Helix-helix parallel interfaces can be characterized by certain combinations of amino acids, which repeatedly occur at core positions a and d (leucine zipper nomenclature) in homologous and nonhomologous proteins and influence interhelical angles. Applied for the prediction of interhelical angles
Y Hathout et al.
Chemical research in toxicology, 9(6), 1044-1049 (1996-09-01)
Interaction of chlorambucil and the glutathione-depleted human placenta pi class glutathione S-transferase (pi GST) results in the formation of a complex between the drug and the protein at physiological pH. This complex is not formed in the presence of glutathione
Liqing Chen et al.
Acta crystallographica. Section D, Biological crystallography, 59(Pt 12), 2211-2217 (2003-12-04)
Glutathione S-transferases (GSTs) are a major family of detoxification enzymes which possess a wide range of substrate specificities. Most organisms possess many GSTs belonging to multiple classes. Interest in GSTs in insects is focused on their role in insecticide resistance;
Markus Perbandt et al.
The Journal of biological chemistry, 280(13), 12630-12636 (2005-01-11)
Onchocerciasis is a debilitating parasitic disease caused by the filarial worm Onchocerca volvulus. Similar to other helminth parasites, O. volvulus is capable of evading the host's immune responses by a variety of defense mechanisms, including the detoxification activities of the
Emilee E Colón-Lorenzo et al.
Frontiers in pharmacology, 11, 246-246 (2020-04-08)
Plasmodium falciparum parasites are increasingly drug-resistant, requiring the search for novel antimalarials with distinct modes of action. Enzymes in the glutathione pathway, including glutathione S-transferase (GST), show promise as novel antimalarial targets. This study aims to better understand the biological

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