跳轉至內容
Merck
全部照片(1)

重要文件

H4632

Sigma-Aldrich

Hemoglobin 马

lyophilized powder

同義詞:

Hb

登入查看組織和合約定價


About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.61

生物源

horse

品質等級

形狀

lyophilized powder

技術

protein quantification: suitable

溶解度

H2O: soluble 10 mg/mL

UniProt登錄號

儲存溫度

2-8°C

基因資訊

一般說明

Hemoglobin is the major component of red blood cells and is responsible for their red color. Its normal concentration in erythrocytes is 34%. The structure of horse hemoglobin was elucidated first. It comprises heme (iron protoporphyrin IX group) and four polypeptide chains. The fetal and adult hemoglobin of horse are structurally identical.

應用

Hemoglobin equine has been used as a standard protein:
  • to test solid-film sampling methodology in Fourier transform infrared spectroscopy (FT-IR) for protein secondary structure determination
  • in capillary reversed-phase liquid chromatography-tandem mass spectrometry (LC/MS/MS) post enzymatic digestion
  • for quantification of hemoglobin content from the planktonic crustacean, Daphnia magna

生化/生理作用

Hemoglobin is the most important respiratory protein of vertebrates by its ability to transport oxygen from the lungs to body tissues and to facilitate the return transport of carbon dioxide. The ferrous-ferric (Fe2+/Fe3+) balance is a physiological indicator of blood oxygenation. Deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to nitric oxide (NO), a vasodilator which enhances blood flow to oxygen-deprived tissues. The fetal and adult hemoglobin from horse display differences in their affinity towards 2,3-diphosphoglycerate (2,3-DPG). Mutation in the globin gene is implicated in sickle cell anemia.
Oxygen transporter, NO scavenger

注意

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Pavel V Bondarenko et al.
Analytical chemistry, 74(18), 4741-4749 (2002-09-28)
In this report, we describe an approach for identification and relative quantitation of individual proteins within mixtures using LC/MS/MS analysis of protein digests. First, the proteins are automatically identified by correlating the tandem mass spectra with peptide sequences from a
A comparative study on STM imaging and electrocatalytic activity of different surfaces modified with flavin adenine dinucleotide
Jingdong Zhang, Qijin Chi, Erkang Wang, Shaojun Dong
Electrochimica Acta, 40, 733-744 (1995)
Alan N Schechter
Blood, 112(10), 3927-3938 (2008-11-08)
Much of our understanding of human physiology, and of many aspects of pathology, has its antecedents in laboratory and clinical studies of hemoglobin. Over the last century, knowledge of the genetics, functions, and diseases of the hemoglobin proteins has been
Alain J Marengo-Rowe
Proceedings (Baylor University. Medical Center), 19(3), 239-245 (2007-01-26)
In 1949 Pauling and his associates showed that sickle cell hemoglobin (HbS) belonged to an abnormal molecular species. In 1958 Ingram, who used a two-dimensional system of electrophoresis and chromatography to break down the hemoglobin molecule into a mixture of
Yan Zhang et al.
Zoological science, 20(9), 1087-1093 (2003-10-28)
The physiological significance of the position and shape of the oxygen equilibrium curve (OEC) of horse hemoglobin (Hb) is considered from the viewpoint of oxygen (O2) transport efficiency and the effectiveness of the Bohr effect. In horse fetal and maternal

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務