跳轉至內容
Merck
全部照片(1)

Key Documents

GW20090F

Sigma-Aldrich

Anti-VLDL antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

登入查看組織和合約定價


About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

chicken

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human

製造商/商標名

Genway 15-288-20090F

技術

indirect ELISA: suitable
western blot: suitable

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... VLDLR(7436)

應用

Anti-VLDL antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

The very-low-density-lipoprotein receptor (VLDLR) is a transmembrane lipoprotein receptor and belongs to low-density-lipoprotein (LDL) receptor family. It is encoded by the VLDLR gene in humans. The LDL receptor gene family members are involved in ligand-mediated signal transduction. VLDLR is involved in the Reelin signaling pathway helping in neuronal migration in the cerebral cortex and cerebellum. It is strongly induced during adipogenesis and actively participates in adipocyte hypertrophy. VLDLR contributes to adipose tissue inflammation and mediates VLDL-induced lipid accumulation. It induces inflammation and ER stress in adipocytes and macrophages. VLDL receptor also plays a role in signaling processes.

外觀

Solution in phosphate buffered saline containing 0.02% sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到適合的產品?  

試用我們的產品選擇工具.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

Andrew Nguyen et al.
The Journal of biological chemistry, 289(3), 1688-1703 (2013-12-03)
Obesity is associated with adipose tissue remodeling, characterized by adipocyte hypertrophy and macrophage infiltration. Previously, we have shown that very low density lipoprotein receptor (VLDLR) is virtually absent in preadipocytes but is strongly induced during adipogenesis and actively participates in
J Nimpf et al.
Biochimica et biophysica acta, 1529(1-3), 287-298 (2000-12-09)
The discovery of an ever growing number of low density lipoprotein (LDL) receptor gene family members has triggered research into many different directions. Here we first summarize the results of classical studies on the role of the LDL receptor in
Praseetha Kizhakkedath et al.
Biochimica et biophysica acta, 1843(12), 2871-2877 (2014-09-01)
Dysequilibrium syndrome (DES, OMIM 224050) is a genetically heterogeneous condition that combines autosomal recessive non-progressive cerebellar ataxia with mental retardation. The subclass dysequilibrium syndrome type 1 (CAMRQ1) has been attributed to mutations in the VLDLR gene encoding the very low
Omar Abuyaman et al.
PloS one, 8(8), e73110-e73110 (2013-09-10)
Cellular uptake of vitamin B12 (B12) demands binding of the vitamin to transcobalamin (TC) and recognition of TC-B12 (holoTC) by the receptor CD320, a receptor expressed in high quantities on human placenta. We have identified a soluble form of CD320

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務