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product name
粒细胞巨噬细胞集落刺激因子 来源于小鼠, GM-CSF, from mouse, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
生物源
mouse
品質等級
重組細胞
expressed in E. coli
化驗
≥97% (SDS-PAGE)
形狀
lyophilized powder
效力
≤0.2 ng/mL EC50 (corresponds to ≥5 × 106 units/mg)
品質
endotoxin tested
分子量
~15 kDa (125 amino acids including N-terminal methionine)
包裝
pkg of 5 and 50 μg
儲存條件
avoid repeated freeze/thaw cycles
技術
cell culture | mammalian: suitable
雜質
≤1 EU/mg
顏色
white
溶解度
water: soluble, clear, colorless
UniProt登錄號
儲存溫度
−20°C
基因資訊
mouse ... CSF2(12981) , Csf2(12981)
生化/生理作用
粒细胞-巨噬细胞集落刺激因子(GM-CSF)是粒细胞、巨噬细胞和嗜酸性粒细胞系的生长和分化因子。GM-CSF 在极低浓度下刺激多能祖细胞集落形成,是造血祖细胞直至成熟的所有分裂中必不可少的存活和增殖因子。它也刺激一些上皮细胞和破骨细胞的生长。GM-CSF 由多种细胞类型(单核细胞、内皮细胞、T 细胞、成纤维细胞、有丝分裂原刺激的 B 细胞和 LPS 刺激的巨噬细胞)产生。GM-CSF 是一种单链糖蛋白,含有 128 个氨基酸,具有保守的二硫键。人和鼠 GM-CSF 的序列同源性约为 54%,生物活性无交叉反应。
外觀
从 10 mM 乙酸 + 250 μg BSA 中冻干。
分析報告
使用小鼠 FDP-1 细胞在培养物中检测了小鼠 GM-CSF 的 EC50 活性。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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