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M6518

Sigma-Aldrich

巨噬细胞集落刺激因子 人

M-CSF, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

同義詞:

MCSF

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About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.77

生物源

human

品質等級

重組細胞

expressed in E. coli

化驗

≥98% (SDS-PAGE and HPLC)

形狀

lyophilized powder

效力

0.500-5.000 ng/mL ED50

品質

endotoxin tested

分子量

dimer 37 kDa

包裝

pkg of 10 μg

技術

cell culture | mammalian: suitable

雜質

≤1.000 EU/μg

顏色

white

UniProt登錄號

儲存溫度

−20°C

基因資訊

human ... CSF1(1435)

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一般說明

Macrophage Colony-Stimulating Factor (M-CSF) is a hematopoietic growth factor, which modulates the proliferation, differentiation and functional activation of monocytes. It is produced by fibroblasts, endothelial cells and bone marrow stromal cells. MCSF stimulates the functions of mature monocytes and macrophages.

應用

Macrophage Colony-Stimulating Factor human has been used for the differentiation of bone marrow-derived macrophages (BMDMs) and human monocyte-derived macrophages (MDMs). It has also been used for cell culture.

生化/生理作用

Macrophage colony-stimulating factor (M-CSF) augments many of the physiological functions of macrophages, and support osteoclast differentiation.

其他說明

159 amino acids including N-terminal methionine (each monomer).

外觀

Lyophilized from a sterile filtered buffered solution.

分析報告

The proliferative activity is tested in culture using the cytokine-dependent murine monocytic cell line M-NFS-60 cells.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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文章

Read article on hematopoietic cytokines and hematopoiesis

Read article on hematopoietic cytokines and hematopoiesis

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