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重要文件

F3301

Sigma-Aldrich

Xa 因子显色底物

chromogenic, ≥90% (HPLC), solid

同義詞:

CH3OCO-D-CHA-Gly-Arg-pNA-AcOH

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About This Item

MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.83

產品名稱

Xa 因子显色底物, solid

化驗

≥90% (HPLC)

品質等級

形狀

solid

分子量

apparent mol wt 622.7

溶解度

methanol: water (1:9): 25 mg/mL

儲存溫度

2-8°C

相關類別

應用

Factor Xa 生色底物已被用于胎盘细胞器蛋白约安巨马陆的factor Xa蛋白酶检测。

生化/生理作用

Factor Xa生色底物含有Bz-Ile-Glu-Gly-Arg-pNA肽序列。Factor Xa会介导底物水解后p-NA 色原体的释放,释放量可以通过光度法测定。

物理性質

人因子 Xa 的 KM 约为 0.8mM

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Probing substrate-induced conformational alterations in adrenoleukodystrophy protein by proteolysis
Guimaraes CP, et al.
Journal of Human Genetics, 50(2), 99-99 (2005)
Pathology consultation on anticoagulation monitoring: factor X-related assays
Wool GD and Lu CM
American Journal of Clinical Pathology, 140(5), 623-634 (2013)
Joannsin, a novel Kunitz-type FXa inhibitor from the venom of Prospirobolus joannsi
Luan N, et al.
Thrombosis and Haemostasis, 117(06), 1031-1039 (2017)
Ning Luan et al.
Thrombosis and haemostasis, 117(6), 1031-1039 (2017-03-10)
The repugnatorial glands of millipedes release various defensive chemical secretions. Although varieties of such defensive secretions have been studied, none of them is protein or peptide. Herein, a novel factor Xa (FXa) inhibitor named joannsin was identified and characterised from repugnatorial glands
Ning Luan et al.
Toxins, 11(12) (2019-12-11)
Elastase is a globular glycoprotein and belongs to the chymotrypsin family. It is involved in several inflammatory cascades on the basis of cleaving the important connective tissue protein elastin, and is strictly regulated to a balance by several endogenous inhibitors.

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