推薦產品
生物源
mouse
品質等級
共軛
FITC conjugate
抗體表格
purified from hybridoma cell culture
抗體產品種類
secondary antibodies
無性繁殖
8c/6-39, monoclonal
形狀
buffered aqueous solution
儲存條件
protect from light
技術
dot immunobinding: 1:64
particle immunofluorescence: 1:32
同型
IgG2a
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
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一般說明
人IgG1单克隆抗体(小鼠IgG2a同种型)来源于小鼠骨髓瘤细胞与免疫小鼠脾细胞融合产生的杂交瘤。
人IgG由四个亚类(1-4)组成,根据它们重链上的不同抗原特异性而区分,分别约占总IgG的65%、30%、5%和4%。每个亚类都有不同的生物和物理化学特性,不同抗原刺激下可优先生成不同的IgG亚类。例如,多糖抗原刺激下产生的主要是IgG2亚类应答,而蛋白抗原则对应IgG1和IgG3抗体。脂多糖激活PBL的IgG2应答和脾脏的IgG1应答。人IgG1是体内和体外产生的破伤风类毒素抗体的主要亚类。
该抗体对人 IgG1 的 Fc 部分具有特异性,与其他 IgG 亚类不反应。IUIS/WHO 研究发现该克隆(也称为 HP-6091)对人 IgG1 具有有价值配置文件反应性和特异性。
生化/生理作用
IgG1和IgG3能粘附单核吞噬细胞。多发性硬化症患者的脑脊液中出现IgG1的异常上升。研究不同类型疾病中IgG亚类的分布模式可揭示其中涉及的免疫过程,从而有助于各种疾病的诊断。
外觀
溶于 0.01 M 磷酸钠缓冲液 (pH 8.0) 中,含有 1% 灭活牛血清白蛋白和 15 mM 叠氮化钠。
免責聲明
除非我们的产品目录或产品随附的其他公司文件中另有说明,否则我们的产品仅用于研究用途,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、体外或体内治疗用途或任何类型的人类或动物消费或应用。
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儲存類別代碼
10 - Combustible liquids
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
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