推薦產品
生物源
synthetic (organic)
化驗
≥99% (HPLC)
形狀
powder
溶解度
water: 50 mg/mL, clear, colorless to very faintly yellow
儲存溫度
−20°C
SMILES 字串
NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](CO)O2
InChI
1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1
InChI 密鑰
CKTSBUTUHBMZGZ-SHYZEUOFSA-N
一般說明
2′-脱氧胞苷(deoxyC)是一种以胞嘧啶作为核碱基的脱氧核苷。存在于血液、粪便和尿液中。
應用
2′-脱氧胞苷已用于：
- 作为布氏锥虫Trypanosoma brucei 胞苷脱氨酶(TbCDA)底物检测其活性
- 作为鼠肿瘤组织间液代谢物液相色谱-质谱法(LC–MS)分离和定量分析的标准品
- 研究自噬在癌基因和DNA复制压力下的作用
生化／生理作用
2′-脱氧胞苷(deoxyC)可磷酸化形成dCTP，再由各种DNA聚合酶或逆转录酶合成DNA。2-脱氧胞苷是脱氧胞苷脱氨酶(EC 3.5.4.14)的底物，该酶可将其转化为2′-脱氧尿苷。2-脱氧胞苷可在脱氧胞苷激酶(DCK)的磷酸化作用下成为核苷酸——脱氧胞苷单磷酸(dCMP)。2-脱氧胞苷可作为头颈癌标志物。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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