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Key Documents

D3447

Sigma-Aldrich

多西环素 盐酸盐

同義詞:

2-并四苯甲酰胺, 4-(二甲氨基)- 1,4,4a,5,5a,6,11,12a-八氢-3,5,10,12,12a-五羟基-6-甲基-1,11-二氧-,盐酸盐(1:1),(4S,4aR,5S,5aR,6R,12aS)-

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About This Item

經驗公式(希爾表示法):
C22H24N2O8 · HCl
CAS號碼:
分子量::
480.90
分類程式碼代碼:
51284028
NACRES:
NA.85

生物源

synthetic

品質等級

形狀

powder

顏色

yellow

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria
mycoplasma
parasites

作用方式

protein synthesis | interferes

儲存溫度

−20°C

InChI

1S/C22H24N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-7,10,14-15,17,25-27,31-32H,23H2,1-3H3;1H/b21-13-;/t7-,10+,14+,15-,17-,22-;/m0./s1

InChI 密鑰

VLUQVUWDECWBTL-UQVCFKGQSA-N

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一般說明

强力霉素是一种四环素类抗生素,通常用于治疗各种感染。它是一种广谱抗生素和抑菌剂。强力霉素具有抗原生动物特性,是体内MMPs(基质金属蛋白酶)的有效抑制剂。

應用

盐酸强力霉素已用于shRNA的诱导表达和表达载体的诱导。

其他說明

保存于密闭容器内,置于干燥通风处。

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Repr. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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存取文件庫

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Long non-coding RNA H19 is aberrantly expressed in multiple malignancies and its expression levels correlate with recurrence, metastasis, and patient survival. Despite numerous reports documenting the role of H19 in carcinogenesis, its contribution to cervical cancer development is still largely
Generation of a PAX6 knockout glioblastoma cell line with changes in cell cycle distribution and sensitivity to oxidative stress
Beate H et al.
BMC Cancer (2018)
David van Dijk et al.
Cell, 174(3), 716-729 (2018-07-03)
Single-cell RNA sequencing technologies suffer from many sources of technical noise, including under-sampling of mRNA molecules, often termed "dropout," which can severely obscure important gene-gene relationships. To address this, we developed MAGIC (Markov affinity-based graph imputation of cells), a method that

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