推薦產品
品質等級
化驗
≥98% (HPLC)
形狀
powder
溶解度
DMSO: >10 mg/mL
儲存溫度
2-8°C
SMILES 字串
Clc1ccc2c(CCc3cccnc3\C2=C4\CCNCC4)c1
InChI
1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2
InChI 密鑰
JAUOIFJMECXRGI-UHFFFAOYSA-N
基因資訊
human ... HRH1(3269)
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應用
Desloratadine has been used to test its effect on embryoid body development in in vitro gastrulation model of P19C5 stem cells. It has also been used as an antihistamine mimic in rats and to treat lung cancer (A549) and glioblastoma (U87) cells in various cellular studies.
生化／生理作用
A non-sedating H1-receptor antagonist, free from antimuscarinic/anticholinergic effects. It has novel antiallergic and anti-inflammatory effects.
Desloratadine is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects.
法律資訊
Clarinex is a registered trademark of Schering Corp.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
390.2 °F - Pensky-Martens closed cup
閃點（°C）
199 °C - Pensky-Martens closed cup
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