CN406-05

Canine Osteoblasts: CnOb (Cryovial)

• 分類程式碼代碼: 41106514
• NACRES: NA.81

屬性

• 生物源: canine bone (normal)
• 包裝: pkg of 500,000 cells
• 製造商／商標名: Cell Applications, Inc
• 增長模式: Adherent
• 染色體組型: 2n = 78
• 形態學: osteoblast
• 技術: cell culture | mammalian: suitable
• 相關疾病: arthritis; osteoporosis
• 運輸包裝: dry ice
• 儲存溫度: −196°C

描述

一般說明

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Canine osteoblasts provide an excellent model system for studies relevant to the skeletal system, including mechanisms of cancerogenesis.

Canine osteoblasts have been used to define a biomarker profile of canine osteosarcoma (Milovancev, 2013), elucidate the roles of oncogenic STAT3 (Fossey, 2009, 2011) and canonical Wnt signaling (Piskun, 2013) pathways, and to develop personalized osteosarcoma treatments by testing Src inhibitor dasatinib (Davis, 2013), procaspase-3 activating compound PAC-1 (Book, 2012), HSP90 inhibitor STA-1474 (McCleese, 2009) and STAT3 inhibitor LLL12 (Couto, 2012, 2013).

Characterization: Positive for bone mineralization.

細胞系來源

Bone

應用

model for skeletal system research, signaling pathways, bone morphogenesis, gene expression, cell activation and proliferation, wound healing, bone formation and regeneration, treatment strategies, tissue engineering, in vitro bone models, mineralization, hormone treatments

成分

Canine Osteoblast Basal Medium containing 10% FBS & 10% DMSO

準備報告

• 1st passage, >500,000 cells in Canine Osteoblast Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 10 doublings

例行更新培養

Please refer to the CnOb Culture Protocol.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable