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Merck
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重要文件

C8974

Sigma-Aldrich

Anti-CD27 antibody produced in goat

affinity isolated antibody, lyophilized powder

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41
共軛:
unconjugated
application:
FACS
Neutral
WB
無性繁殖:
polyclonal
物種活性:
human
citations:
1
技術:
flow cytometry: suitable
neutralization: 2.25-9.0 μg/mL
western blot: 0.1-0.2 μg/mL

生物源

goat

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

lyophilized powder

物種活性

human

技術

flow cytometry: suitable
neutralization: 2.25-9.0 μg/mL
western blot: 0.1-0.2 μg/mL

UniProt登錄號

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... CD27(939)

一般說明

CD27, a member of tumour necrosis factor receptor superfamily is mainly responsible for regulation of cell proliferation and cell death. CD27 and its ligand CD70 expresses mainly on lymphocytes. Anti-CD27 antibody can be used in immunoblotting and flow cytometry. It can also be used in immunopresipitating CD27. Anti-CD27 antibody reacts specifically with human CD27 and not with recombinant human CD30, recombinant human NGF R, recombinant human soluble TNF RI, or recombinant human soluble TNF RII.

免疫原

recombinant human CD27 extracellular domain expressed in Sf2I insect cells.

應用

Anti-CD27 antibody can be used in neutralization, immunoblotting and indirect flow cytometry assays.

外觀

Lyophilized from 0.2 μm filtered solution of phosphate buffered saline with 5% trehalose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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K V Prasad et al.
Proceedings of the National Academy of Sciences of the United States of America, 94(12), 6346-6351 (1997-06-10)
Members of the tumor necrosis factor receptor (TNFR) superfamily are important for cell growth and survival. In addition to providing costimulatory signals for cell proliferation, ligation of both TNFR1 and Fas can result in programmed cell death or apoptosis. The
Eleanor M P Wilson et al.
The Journal of infectious diseases, 210(9), 1396-1406 (2014-05-13)
Soluble biomarkers of inflammation predict non-AIDS related morbidity and mortality among human immunodeficiency virus (HIV)-infected persons. Exploring associations between plasma biomarkers and cellular phenotypes may identify sources of excess inflammation. Plasma biomarkers (interleukin 6 [IL-6] level, D-dimer level, high-sensitivity C-reactive

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