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Key Documents

B7632

Sigma-Aldrich

N-苯甲酰基-Phe-Val-Arg-硝基苯胺 盐酸盐

chromogenic, protease substrate, ≥98% (TLC), powder

同義詞:

N-苯甲酰基-L-苯丙氨酰-L-缬氨酰-L-精氨酸-4-硝基苯胺 盐酸盐

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About This Item

經驗公式(希爾表示法):
C33H40N8O6 · HCl
CAS號碼:
分子量::
681.18
Beilstein:
3027332
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32

product name

N-苯甲酰基-Phe-Val-Arg-硝基苯胺 盐酸盐, protease substrate

品質等級

化驗

≥98% (TLC)

形狀

powder

溶解度

methanol: 20 mg/mL, clear, colorless to light yellow

儲存溫度

−20°C

SMILES 字串

Cl.CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)Nc3ccc(cc3)[N+]([O-])=O

InChI

1S/C33H40N8O6.ClH/c1-21(2)28(40-31(44)27(20-22-10-5-3-6-11-22)39-29(42)23-12-7-4-8-13-23)32(45)38-26(14-9-19-36-33(34)35)30(43)37-24-15-17-25(18-16-24)41(46)47;/h3-8,10-13,15-18,21,26-28H,9,14,19-20H2,1-2H3,(H,37,43)(H,38,45)(H,39,42)(H,40,44)(H4,34,35,36);1H/t26-,27-,28-;/m0./s1

InChI 密鑰

PYVSMZDQQUZGPF-JAQKLANPSA-N

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一般說明

N-苯甲酰基-Phe-Val-Arg-硝基苯胺是显色蛋白酶底物。

應用

  • N

  • -苯甲酰基-Phe-Val-Arg-硝基苯胺盐酸盐已作为底物:用于凝血酶菌丝
  • 的可溶性和颗粒部分中的胰蛋白酶样酶,来自蛇毒的重组和天然巴曲酶
  • 用于酰胺分解活性测定中的纤溶酶aprE2

包裝

无底玻璃瓶。内含物装在插入的融合锥内。

基底

胰蛋白酶,凝血酶和蛇毒凝血酶的底物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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存取文件庫

Inhibition of human coagulation factor Xa by thrombin substrates.
C L Orthner et al.
Thrombosis research, 23(6), 533-539 (1981-09-15)
Heparin and protease inhibition. II. The role of heparin in the ATIII inactivation of thrombin, plasmin, and trypsin.
G F Smith et al.
Thrombosis research, 22(1-2), 115-133 (1981-04-01)
Synthesis of Bz-Phe(p-No2)-Val-Arg-pNA-and its specificity to thrombin-like enzymes: similarity of a commercial product S-2160 to the nitrated compound.
K Takada et al.
Thrombosis research, 20(5-6), 533-572 (1980-12-01)
Hydrolysis of N-alpha-benzoyl-L-phenylalanyl-L-valyl-L-arginine-p-nitroanilide by human alpha thrombin in the presence of heparin.
M J Griffith et al.
Thrombosis research, 17(1-2), 83-90 (1980-01-01)
Y Komori et al.
Biochimica et biophysica acta, 829(1), 127-130 (1985-05-20)
Hemorrhagic proteinase, HTb, isolated from Crotalus atrox (western diamondback rattlesnake) venom was studied for its specificity. HTb showed fibrinogenase activity, hydrolyzing the A alpha chain of fibrinogen first, followed by the cleavage of the B beta chain. HTb is different

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