跳轉至內容
Merck
全部照片(3)

Key Documents

更多文件

A9789

Sigma-Aldrich

茴香霉素 来源于浅灰链霉菌

≥98% (HPLC), solid

同義詞:

(2R,3S,4S)-2-(4-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate, 2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate, Flagecidin

登入查看組織和合約定價
全部照片(3)

About This Item

經驗公式（希爾表示法）:
C14H19NO4
CAS號碼:
22862-76-6
分子量：:
265.30
Beilstein:
20705
EC號碼:
245-269-7
MDL號碼:
MFCD00077650
分類程式碼代碼:
12352200
PubChem物質ID:
24891496
NACRES:
NA.77

品質等級

300

化驗

≥98% (HPLC)

形狀

solid

顏色

white to faint yellow

溶解度

H2O: 2 mg/mL (Aqueous solutions are stable over a wide range of pH at room temperature.)
DMSO: 20 mg/mL
methanol: 20 mg/mL

抗生素活性譜

neoplastics

作用方式

protein synthesis | interferes

儲存溫度

2-8°C

SMILES 字串

COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)cc1

InChI

1S/C14H19NO4/c1-9(16)19-14-12(15-8-13(14)17)7-10-3-5-11(18-2)6-4-10/h3-6,12-15,17H,7-8H2,1-2H3/t12-,13+,14+/m1/s1

InChI 密鑰

YKJYKKNCCRKFSL-RDBSUJKOSA-N

尋找類似的產品？ 前往 產品比較指南

相關類別

生化／生理作用

Antibiotic isolated from Streptomyces griseolus that inhibits protein synthesis. Acts by inhibiting peptidyl transferase activity in eukaryote ribosomes. Reported to induce apoptosis in a variety of cells including promyelocytic leukemia cells, Jurkat cells, ventricular myocytes, and colon adenocarcinoma cells. Initiates intracellular signals and immediate early gene induction. Selective signaling agonist. Potent Jun-NH2 terminal kinase (JNK) agonist. Activates mitogen-activated protein (MAP) kinases (JNK/SAPK and p38/RK). Antiprotozoal agent.

注意

吸湿

象形圖

Skull and crossbones
GHS06

訊號詞

Danger

危險聲明

H301

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

已經擁有該產品？

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

J Daubriac et al.
Cell death and differentiation, 16(8), 1146-1155 (2009-04-04)
Pleural fluid accumulation is a frequent clinical observation in diffuse malignant pleural mesothelioma (MPM). The cytological analysis of pleural fluid often reveals the presence of free spheroid aggregates of malignant cells, giving rise to the question of the ability of
Verónica de la Fuente et al.
Scientific reports, 9(1), 12157-12157 (2019-08-23)
Memories are a product of the concerted activity of many brain areas. Deregulation of consolidation and reprocessing of mnemonic traces that encode fearful experiences might result in fear-related psychopathologies. Here, we assessed how pre-established memories change with experience, particularly the
Sovan Sarkar et al.
Nature chemical biology, 3(6), 331-338 (2007-05-09)
The target of rapamycin proteins regulate various cellular processes including autophagy, which may play a protective role in certain neurodegenerative and infectious diseases. Here we show that a primary small-molecule screen in yeast yields novel small-molecule modulators of mammalian autophagy.
Gretchen Ehrenkaufer et al.
PLoS neglected tropical diseases, 14(3), e0008150-e0008150 (2020-03-21)
Parasitic infections are a major source of human suffering, mortality, and economic loss, but drug development for these diseases has been stymied by the significant expense involved in bringing a drug though clinical trials and to market. Identification of single
Stéphane Delmas et al.
Molecular microbiology, 87(1), 168-179 (2012-11-14)
In prokaryotes the genome is organized in a dynamic structure called the nucleoid, which is embedded in the cytoplasm. We show here that in the archaeon Haloferax volcanii, compaction and reorganization of the nucleoid is induced by stresses that damage
查看所有相關論文

我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務