推薦產品
生物源
rabbit
品質等級
共軛
agarose conjugate
抗體表格
IgG fraction of antiserum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
PBS suspension
分子量
antigen 27.5 kDa
應無反應活性
porcine, bovine, human, rabbit, rat
技術
ELISA: suitable
immunoprecipitation (IP): suitable
運輸包裝
wet ice
儲存溫度
2-8°C
目標翻譯後修改
unmodified
基因資訊
human ... GSTP1(2950)
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一般說明
该抗体对日本血吸虫 谷胱甘肽-S-转移酶的天然型和变性-还原型均具有特异性 。抗 GST 可用于各种免疫分析，以鉴定 GST 融合蛋白的表达。
Glutathione-S-transferases (GSTs) are dimeric proteins, which belongs to phase II detoxification enzymes family. The highly polymorphic human cytosolic GSTs are divided into six classes, such as, α, μ, ω, π, θ, and ζ.
免疫原
日本血吸虫 的重组 GST 在 大肠杆菌中表达 。
應用
Immunoprecipitation was performed on NIH 3T3 cells transiently transfected with GST fusion proteins. IP was performed using agarose-linked rabbit anti-GST IgG with mixing for 2 hours at 4 degrees.
Rabbit Anti-Glutathione-S-Transferase (GST)-Agarose antibody can be used for ELISA, immunoaffinity purification and immunoprecipitation assays.
生化／生理作用
Glutathione-S-transferases (GSTs) can catalyse the conjugation of glutathione (GSH) to various endogenous and exogenous electrophilic compounds. The π and μ classes of GSTs controls the mitogen-activated protein (MAP) kinase pathway. It can also serve as transport proteins.
外觀
Suspension in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
準備報告
Prepared by coupling cyanogen bromide-activated agarose at 7-8 mg antibody per mL resin volume.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Jessica Gagnon et al.
Epigenetics, 10(8), 677-691 (2015-06-16)
O-GlcNAcylation is a posttranslational modification catalyzed by the O-Linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) and reversed by O-GlcNAcase (OGA). Numerous transcriptional regulators, including chromatin modifying enzymes, transcription factors, and co-factors, are targeted by O-GlcNAcylation, indicating that this modification is central for
Metabolism of xenobiotics of human environments
Progress in Molecular Biology and Translational Science, 112, 31-88 (2012)
Clinical pathology in non-clinical toxicology testing
Haschek and Rousseaux's Handbook of Toxicologic Pathology, 112(47), 565-594 (2013)
The role of glutathione-S-transferase in anti-cancer drug resistance
Townsend D M and Tew K D
Oncogene, 22(47), 7369-7369 (2003)
Xun Shang et al.
The Journal of biological chemistry, 282(12), 8801-8811 (2007-02-03)
p200 RhoGAP, a member of the Rho GTPase-activating protein (RhoGAP) family, was previously implicated in the regulation of neurite outgrowth through its RhoGAP activity. Here we show that ectopic expression of p200 RhoGAP stimulates fibroblast cell proliferation and cell cycle
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