A1774

阿米卡星 二硫酸盐

potency: 674-786 μg per mg (as amikacin base)

• 同義詞: (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide disulfate, Antibiotic BB-K8 sulfate
• 經驗公式（希爾表示法）: C₂₂H₄₃N₅O₁₃ · 2H₂SO₄
• CAS號碼: 39831-55-5
• 分子量：: 781.76
• Beilstein: 6172633
• EC號碼: 254-648-6
• MDL號碼: MFCD00167475
• 分類程式碼代碼: 51281632
• PubChem物質ID: 24890586
• NACRES: NA.85

屬性

• 生物源: synthetic
• 形狀: powder or crystals
• 效力: 674-786 μg per mg (as amikacin base)
• 顏色: white to off-white
• 抗生素活性譜: Gram-negative bacteria; mycobacteria
• 作用方式: protein synthesis | interferes
• 儲存溫度: 2-8°C
• SMILES 字串: OS(O)(=O)=O.OS(O)(=O)=O.NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O
• InChI: 1S/C22H43N5O13.2H2O4S/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21;2*1-5(2,3)4/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36);2*(H2,1,2,3,4)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+;;/m0../s1
• InChI 密鑰: FXKSEJFHKVNEFI-GCZBSULCSA-N

描述

一般說明

Chemical structure: aminoglycoside

應用

Amikacin is an aminoglycoside antibiotic commonly used in the treatment of drug-resistant mycobacteria . It is used to study organism-directed delivery of antibiotics as well as drug resistance .

生化／生理作用

Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading.

包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

其他說明

Keep container tightly closed in a dry and well-ventilated place.

安全資訊

• 象形圖: GHS08,GHS07
• 訊號詞: Warning
• 危險聲明: H317,H361fd
• 防範說明: P202 - P261 - P272 - P280 - P302 + P352 - P308 + P313
• 危險分類: Repr. 2 - Skin Sens. 1
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)