推薦產品
品質等級
化驗
≥98% (HPLC)
形狀
powder
儲存條件
desiccated
顏色
white to beige
溶解度
H2O: 10 mg/mL
λmax
258 nm
儲存溫度
−20°C
SMILES 字串
CCN(CC)CC.Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP(O)(=S)O[C@H]4[C@H]3O
InChI
1S/C10H12N5O5PS.C6H15N/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(19-10)1-18-21(17,22)20-7;1-4-7(5-2)6-3/h2-4,6-7,10,16H,1H2,(H,17,22)(H2,11,12,13);4-6H2,1-3H3/t4-,6-,7-,10-,21?;/m1./s1
InChI 密鑰
OXIPZMKSNMRTIV-NVGWRVNNSA-N
應用
Rp-腺苷-3′,5′-环一硫代磷酸三乙酯铵盐已被用作cAMP的拮抗剂,以阻断cAMP-PKA信号通路。
生化/生理作用
Rp-腺苷-3′,5′-环一硫代磷酸三乙酯铵盐能够抑制蛋白激酶A(PKA)。
腺苷-3′,5′-环状单硫代磷酸酯 Rp-非对映异构体。cAMP(cAMP 依赖性蛋白激酶I 和 II)激活作用的特异性膜渗透性抑制剂;对环核苷酸磷酸二酯酶具有抗性;在许多系统中阻断 cAMP 介导的作用。
特點和優勢
这种化合物是环核苷酸研究的特色产品。点击此处发现更多特色环核苷酸产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
注意
非常吸湿。储存于干燥处。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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