推薦產品
生物源
Bacillus sp. (B. fastidiosus)
品質等級
形狀
powder
品質
lyophilized
比活性
~9 U/mg
儲存條件
dry at room temperature
濃度
90—100%
顏色
white to faint beige
溶解度
5 mg/mL, clear, colorless to very faintly yellow (in enzyme dilution buffer)
應用
detection
儲存溫度
−20°C
SMILES 字串
N.OCC1OC(C(O)C1OP(O)(=O)OCC2OC(C(O)C2O)N3C=CC(=O)NC3=O)N4C=CC(=O)NC4=O
InChI
1S/C18H23N4O14P.H3N/c23-5-7-14(13(28)16(34-7)22-4-2-10(25)20-18(22)30)36-37(31,32)33-6-8-11(26)12(27)15(35-8)21-3-1-9(24)19-17(21)29;/h1-4,7-8,11-16,23,26-28H,5-6H2,(H,31,32)(H,19,24,29)(H,20,25,30);1H3
InChI 密鑰
VPXDHZMLJOJKOX-UHFFFAOYSA-N
一般說明
尿酸酶存在于古菌、细菌和真核生物等诸多生物中。尿酸酶主要来源于肠道菌群,是一种由相同的34 kDa亚基组成的同源四聚体酶。
研究领域:细胞信号传导
應用
尿酸酶可用于测定生物液体中的尿酸。可能有助于利用分光光度法测定嘌呤和嘌呤核苷。
生化/生理作用
尿酸酶可催化尿酸氧化为5-羟基异尿酸,随后形成(S)-尿囊素。 它参与嘌呤代谢、尿酸盐降解和(S)-尿囊素形成。人体缺乏尿酸酶会造成严重的生理及病理影响。它与血清尿酸水平提高有关,导致尿酸结晶相关疾病(如痛风症)风险上升。尿酸酶是治疗高尿酸血症相关疾病(如痛风症)的重要靶标。
單位定義
在pH 9.1和37 °C的条件下,1 U相当于在每分钟内氧化1 μmole 尿酸所需的酶量。
其他說明
用于测定生物液体中的尿酸;用于分光光度法测定嘌呤和嘌呤核苷。
訊號詞
Danger
危險聲明
危險分類
Eye Irrit. 2 - Repr. 1B - Resp. Sens. 1
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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