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77151

Sigma-Aldrich

胃蛋白酶 来源于猪胃粘膜

powder, slightly beige, 1200-2400 U/mg

同義詞:

胃液素 来源于猪胃, 胃蛋白酶 A

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About This Item

CAS號碼:
酶委員會編號:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
eCl@ss:
42010127
NACRES:
NA.54

形狀

powder

比活性

1200-2400 U/mg

分子量

35 kDa

顏色

slightly beige

UniProt登錄號

儲存溫度

2-8°C

基因資訊

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應用

胃蛋白酶切割可用于产生抗体的F(ab′)2 片段。有关胃蛋白酶的更多信息,请访问 www.sigma-aldrich.com/enzymeexplorer

生化/生理作用

优先裂解:P1 和 P1′ 位的疏水性和芳族残基。降解胰岛素 β 链中的 Phe-Val、Gln-His、Glu-Ala、Ala-Leu、Leu-Tyr、Tyr-Leu、Gly-Phe、Phe-Phe 和 Phe-Tyr 键

單位定義

在pH 2.0和37℃条件下,1 U对应于每分钟使280 nm处的吸光度增加0.001的酶量(血红蛋白,货号51290,作为底物)如上所述的15′000吸光度-U相当于 ∼1 Bergmeyer-U。 1 Bergmeyer-U是在pH 2.0和37℃条件下水解1 μmmol乙酰基-L-苯基-3,5-二碘代-L-酪氨酸的酶量

分析報告

最适pH值为2-4。在4 M尿素和3 M盐酸胍中可保持活性。在60°C时稳定。胃蛋白酶在pH 8.0-8.5下发生不可逆灭活。

其他說明

可能会涉及到销售限制

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險分類

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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