推薦產品
重組細胞
expressed in E. coli
形狀
liquid
比活性
≥500 U/mL
技術
cell based assay: suitable
顏色
light brownish-yellow to brown-green
適合性
suitable for molecular biology
應用
life science and biopharma
儲存溫度
−20°C
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一般說明
研究领域：神经科学
醇脱氢酶的同源二聚体结构在C端具有辅酶结合结构域，在N末端具有催化结构域。活动部位位于域间裂隙。NAD+在活性位点的结合会引起构象变化，从而形成醇底物的结合位点。
醇脱氢酶的同源二聚体结构在C端具有辅酶结合结构域，在N末端具有催化结构域。活动部位位于域间裂隙。NAD+在活性位点的结合会引起构象变化，从而形成醇底物的结合位点。
應用
醇脱氢酶（ADH）被用于逆转精神分裂症断裂基因1（DISC1-FL）和DB7细胞裂解物中缺乏的3-[4,5-二甲基噻唑-2-基]-2,5二苯基四唑溴化物（MTT）测定的减少。
生化／生理作用
醇脱氢酶催化醇氧化转化为醛。醇脱氢酶（ADH）催化的乙醇代谢引发活性氧（ROS）和一氧化氮（NO）的产生，导致线粒体和细胞蛋白氧化损伤，并进一步与神经炎症和神经系统疾病的发生有关。
單位定義
一个单位对应于在pH 7.0和30℃（NADPH作为辅助因子）下，每分钟减少1 μmol丙酮所需的酶量
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2
儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves
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