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重要文件

47608

Sigma-Aldrich

甲醛 溶液

for molecular biology, BioReagent, ≥36.0% in H2O (T)

同義詞:

Formol, 甲醛, 福尔马林

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About This Item

線性公式:
HCHO
CAS號碼:
分子量::
30.03
Beilstein:
1209228
MDL號碼:
分類程式碼代碼:
12352114
PubChem物質ID:
NACRES:
NA.52

等級

for molecular biology

品質等級

蒸汽密度

1.03 (vs air)

蒸汽壓力

52 mmHg ( 37 °C)

產品線

BioReagent

形狀

liquid

自燃溫度

572 °F

包含

~10% methanol as stabilizer

濃度

≥36.0% in H2O (T)
36.0-38.0% (aldehyde method)

技術

electrophoresis: suitable

雜質

≤0.03% free acid (as HCOOH)

燃燒殘留物

≤0.05% (as SO4)

pH值

2.8-4.0

密度

1.09 g/mL at 20 °C
1.09 g/mL at 25 °C (lit.)

負離子痕跡

chloride (Cl-): ≤10 mg/kg
sulfate (SO42-): ≤20 mg/kg

正離子痕跡

Ca: ≤5 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Na: ≤100 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Zn: ≤1 mg/mL

&lambda ;

2 M in H2O

紫外吸收

λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01

適合性

in accordance for electrophoresis of RNA in agarose gels

儲存溫度

room temp

SMILES 字串

[H]C([H])=O

InChI

1S/CH2O/c1-2/h1H2

InChI 密鑰

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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一般說明

甲醛是一种分子生物学试剂,当掺入琼脂糖凝胶时,在电泳过程中使RNA变性。
它是一种脂肪族醛,在工业上广泛用于合成几种化学品,如三聚氰胺甲醛、脲醛、酚甲醛和工业树脂、多聚甲醛、多元醇、螯合剂、缓释肥料、1,4-丁二醇和六亚甲基四胺。

應用

甲醛溶液适用于:
  • RNA分子的变性和分离
  • 抗菌治疗
  • 细胞固定
甲醛溶液已被用于:
  • 人精原干细胞移植(SSCT)的固定。
  • 在染色质免疫沉淀过程中交联T细胞急性淋巴细胞白血病蛋白/DNA复合体。
  • 斑马鱼幼体中性粒细胞染色固定。

注意

可能含有沉淀(多聚甲醛)

原則

甲醛能够破坏RNA的二级结构,并帮助实现基于电荷迁移的RNA种类分离和鉴定。

訊號詞

Danger

危險分類

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3

標靶器官

Eyes,Central nervous system, Respiratory system

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

133.0 °F - closed cup

閃點(°C)

56.11 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Jin Qian et al.
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Interferon-induced transmembrane (IFITM) proteins inhibit the entry of a large number of viruses. Not surprisingly, many viruses are refractory to this inhibition. In this study, we report that different strains of HIV and SIV are inhibited by human IFITM proteins
Y Jiang et al.
Oncogene, 34(50), 6079-6091 (2015-03-10)
Epstein-Barr virus (EBV) causes human lymphoid malignancies, and the EBV product latent membrane protein 1 (LMP1) has been identified as an oncogene in epithelial carcinomas such as nasopharyngeal carcinoma (NPC). EBV can epigenetically reprogram lymphocyte-specific processes and induce cell immortalization.
John N Griffin et al.
PLoS genetics, 11(3), e1005018-e1005018 (2015-03-11)
The production of ribosomes is ubiquitous and fundamental to life. As such, it is surprising that defects in ribosome biogenesis underlie a growing number of symptomatically distinct inherited disorders, collectively called ribosomopathies. We previously determined that the nucleolar protein, NOL11
Dannis G van Vuurden et al.
Neuro-oncology, 16(7), 946-959 (2014-01-29)
Glial brain tumors cause considerable mortality and morbidity in children and adults. Innovative targets for therapy are needed to improve survival and reduce long-term sequelae. The aim of this study was to find a candidate tumor-promoting protein, abundantly expressed in
Kerstin Hahn et al.
PloS one, 10(11), e0141824-e0141824 (2015-11-12)
Clinical, pathological and genetic examination revealed an as yet uncharacterized juvenile-onset neuroaxonal dystrophy (NAD) in Spanish water dogs. Affected dogs presented with various neurological deficits including gait abnormalities and behavioral deficits. Histopathology demonstrated spheroid formation accentuated in the grey matter

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