468R-1

Claudin-4 (EP417) Rabbit Monoclonal Primary Antibody

• 分類程式碼代碼: 12352203

屬性

• 生物源: rabbit
• 品質等級: 100; 500
• 共軛: unconjugated
• 抗體表格: culture supernatant
• 抗體產品種類: primary antibodies
• 無性繁殖: EP417, monoclonal
• 描述: For In Vitro Diagnostic Use in Select Regions
• 形狀: buffered aqueous solution
• 物種活性: human
• 包裝: vial of 0.1 mL concentrate (468R-14); vial of 0.1 mL concentrate Research Use Only (468R-14-RUO); vial of 0.5 mL concentrate (468R-15); vial of 1.0 mL concentrate (468R-16); vial of 1.0 mL concentrate Research Use Only (468R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (468R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (468R-17); vial of 7.0 mL pre-dilute ready-to-use (468R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (468R-18-RUO)
• 製造商／商標名: Cell Marque^™
• 技術: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 (concentrated)
• 同型: IgG
• 控制: lung adenocarcinoma
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 視覺化: membranous
• 基因資訊: human ... CLDN4(1364)

描述

一般說明

The claudin-family proteins are a group of tight-junction membranous proteins responsible for paracellular molecular flow between adjacent cells of the epithelium.¹ In normal kidney, claudin-4 plays a key role in paracellular ion reabsorption.² Claudin-4 is expressed in most epithelial cells yet is absent in mesothelial cells, making it of great use in characterizing epithelial malignincies.³ Immunohistochemical identification of this antigen may help identify poorly differentiated lung adenocarcinoma from lesions of mesothelial origin.⁴ Likewise, identification of claudin-4 expression by IHC may be useful in characterizing breast and endometrial lesions.^5,6

品質

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

準備報告

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其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2