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Merck
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重要文件

356R-1

Sigma-Aldrich

Cytokeratin 5 & 6 (EP24 & EP67) Rabbit Monoclonal Primary Antibody

同義詞:

CK 5/6, cytokeratin 5/6

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

EP24 & EP67, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (356R-14)
vial of 0.1 mL concentrate Research Use Only (356R-14-RUO)
vial of 0.5 mL concentrate (356R-15)
vial of 1.0 mL concentrate (356R-16)
vial of 1.0 mL concentrate Research Use Only (356R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (356R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (356R-17)
vial of 7.0 mL pre-dilute ready-to-use (356R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (356R-18-RUO)

製造商／商標名

Cell Marque™

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)

控制

mesothelioma, prostate, squamous cell carcinoma ((lung))

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

cytoplasmic

基因資訊

human ... KRT5(3852)

相關類別

一般說明

Twenty identified cytokeratins make up a complex family of intermediate filaments.1 Cytokeratin 5 (58kDa) & cytokeratin 6 (56kDa) are type II high molecular weight keratins that are expressed in a broad range of normal tissues including breast, prostate, mesothelium, skin and esophagus.1-3 Anti-Cytokeratin 5 & 6 is a useful immunohistochemical marker in the identification of mesothelioma and lung squamous cell carcinoma.1

品質

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

聯結

Cytokeratin 5 & 6 Positive Control Slides, Product No. 356S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris buffer, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide

準備報告

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

Download the latest released IFU
Note: This IFU may not apply to your specific product lot.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析證明 (COA)

Lot/Batch Number

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R Lersch et al.
Molecular and cellular biology, 9(9), 3685-3697 (1989-09-01)
The mitotically active basal layers of most stratified squamous epithelia express 10 to 30% of their total protein as keratin. The two keratins specifically expressed in these cells are the type II keratin K5 (58 kilodaltons) and its corresponding partner
Role of immunohistochemistry in distinguishing epithelial peritoneal mesotheliomas from peritoneal and ovarian serous carcinomas.
Ordo?ez, N.G.
Modern Pathology, 15, 6-10 (2002)
K Takahashi et al.
The Journal of biological chemistry, 270(31), 18581-18592 (1995-08-04)
The human type II keratin 6 (K6; 56 kDa) is expressed in a heterogeneous array of epithelial tissues under normal conditions, but is better known for its strong induction in stratified epithelia that feature an enhanced cell proliferation rate or
N G Ordóñez
The American journal of surgical pathology, 22(10), 1215-1221 (1998-10-20)
The immunohistochemical diagnosis of mesothelioma is commonly made by using a battery of antibodies that reacts with lung adenocarcinomas but not with epithelial mesotheliomas. Only recently have markers that are often expressed in mesotheliomas but not in adenocarcinomas been recognized.

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