356M-1

Cytokeratin 5 & 6 (D5 & 16B4) Mouse Monoclonal Antibody

• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100; 500
• 共軛: unconjugated
• 抗體表格: culture supernatant
• 抗體產品種類: primary antibodies
• 無性繁殖: D5 & 16B4, monoclonal
• 描述: For In Vitro Diagnostic Use in Select Regions (See Chart)
• 形狀: buffered aqueous solution
• 物種活性: human
• 包裝: vial of 0.1 mL concentrate (356M-14); vial of 0.5 mL concentrate (356M-15); bottle of 1.0 mL predilute (356M-17); vial of 1.0 mL concentrate (356M-16); bottle of 7.0 mL predilute (356M-18)
• 製造商／商標名: Cell Marque^™
• 技術: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
• 同型: IgG1
• 控制: mesothelioma
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 視覺化: cytoplasmic
• 基因資訊: human ... KRT5(3852)

描述

一般說明

Anti-CK 5 & 6 positivity is seen in 65% to 100% of epithelioid mesotheliomas, in 0% to 19% of lung adenocarcinomas, and in 22% to 80% of serous carcinoma of the ovary and peritoneum. Keratin 5 & 6 expression in lung adenocarcinoma is not common, and when it occurs, the reaction is usually confined to small focal areas or scattered cells. The most probable cause of this finding is the presence of squamous differentiation of lung adenocarcinoma. Anti-CK 5 & 6 positivity has been useful in recognizing squamous cell carcinoma of the skin. Less than 10% of carcinomas of the breast, colon, and prostate stain positively for this marker. Anti-CK 5 & 6 has also been used successfully as a myoepithelial cell marker in the prostate and breast to determine malignancy. Anti-CK 5 & 6 is a useful marker to distinguish lung squamous cell carcinoma from lung adenocarcinoma and large cell carcinoma within a panel including antibodies against TTF-1, Napsin A, p63, SOX-2, desmocollin3, and desmoglein3.

品質

IVD

IVD

IVD

RUO

聯結

Cytokeratin 5 & 6 Positive Control Slides, Product No. 356S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany