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Key Documents

352M-9

Sigma-Aldrich

Napsin A (MRQ-60) Mouse Monoclonal Antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

MRQ-60, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (352M-94)
vial of 0.5 mL concentrate (352M-95)
bottle of 1.0 mL predilute (352M-97)
vial of 1.0 mL concentrate (352M-96)
bottle of 7.0 mL predilute (352M-98)

製造商/商標名

Cell Marque

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同型

IgG1κ

控制

lung adenocarcinoma, renal cell carcinoma

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

cytoplasmic

基因資訊

human ... NAPSA(9476)

一般說明

Napsin is a pepsin-like aspartic proteinase in the A1 clan of the AA clade ofproteinases. Napsin A is involved in processing propeptide pulmonary surfactant protein B(proSP-B) in the lung. In normal, benign tissue, Napsin A has expressed in type II pneumocytesof the lung and proximal tubules of the kidney. Napsin A is a useful marker for lungadenocarcinoma.

品質


IVD

IVD

IVD

RUO

聯結

Napsin A Positive Control Slides, Product No. 352S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Frank Brasch et al.
The Journal of biological chemistry, 278(49), 49006-49014 (2003-09-18)
Surfactant protein B (SP-B) is a critical component of pulmonary surfactant, and a deficiency of active SP-B results in fatal respiratory failure. SP-B is synthesized by type-II pneumocytes as a 42-kDa propeptide (proSP-B), which is posttranslationally processed to an 8-kDa
Jaishree Jagirdar
Archives of pathology & laboratory medicine, 132(3), 384-396 (2008-03-06)
Immunohistochemistry is a very valuable and often used tool in the differential diagnosis of lung carcinomas whether primary or secondary to the lung. The most useful application is in distinguishing primary lung tumors from metastatic tumors to the lung from
Justin A Bishop et al.
Human pathology, 41(1), 20-25 (2009-09-11)
Recent advances in the treatment of pulmonary adenocarcinoma have increased the need for accurate typing of non-small cell carcinomas. Immunohistochemistry for thyroid transcription factor-1 is widely used in the diagnosis of pulmonary adenocarcinomas because it marks approximately 75% of lung
Jiqing Ye et al.
Applied immunohistochemistry & molecular morphology : AIMM, 19(4), 313-317 (2011-04-06)
Differentiation of primary from metastatic adenocarcinoma in the lung can be challenging, and it demands sensitive and specific biomarkers, especially when the tissue for diagnosis is limited. Thyroid transcription factor-1 (TTF-1) has been considered a reliable marker for adenocarcinoma of
Annika Dejmek et al.
Diagnostic cytopathology, 35(8), 493-497 (2007-07-20)
The purpose of this study was to test napsin A as a diagnostic marker of metastatic lung adenocarcinoma in pleural effusions, and to compare its performance with TTF-1. Napsin A and TTF-1 reactivities were determined immunohistochemically on formalin-fixed paraffin embedded

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