30290

Cytidine 5′-diphosphocholine sodium salt hydrate

≥99.0% (HPLC)

• 同義詞: CDP-choline-Na
• 經驗公式（希爾表示法）: C₁₄H₂₅N₄NaO₁₁P₂ · xH₂O
• CAS號碼: 33818-15-4
• 分子量：: 510.31 (anhydrous basis)
• Beilstein: 4110040
• MDL號碼: MFCD00150508
• 分類程式碼代碼: 41106305
• PubChem物質ID: 57648419
• NACRES: NA.51

屬性

• 生物源: synthetic
• 化驗: ≥99.0% (HPLC)
• 形狀: powder
• 雜質: ≤8% water
• 儲存溫度: 2-8°C
• SMILES 字串: [Na+].C[N+](C)(C)CCOP([O-])(=O)OP([O-])(=O)OCC1OC([C@H](O)[C@@H]1O)N2C=CC(N)=NC2=O
• InChI: 1S/C14H26N4O11P2.Na/c1-18(2,3)6-7-26-30(22,23)29-31(24,25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21;/h4-5,9,11-13,19-20H,6-8H2,1-3H3,(H3-,15,16,21,22,23,24,25);/q;+1/p-1/t9?,11-,12-,13?;/m1./s1
• InChI 密鑰: YWAFNFGRBBBSPD-MBWJOHGMSA-M

描述

應用

Cytidine 5′-diphosphocholine (CDP-choline) is generated by choline-phosphate cytidylyltransferase EC 2.7.7.15 in support of the synthesis of phosphatidylcholine. CDP-choline is being used in studies of its affects on neurorecovery.

Cytidine 5′-diphosphocholine sodium salt hydrate has been used as a component of the mixture during the ribonucleotide reductase (RNR) assay in mouse primary pancreatic acinar cells.

生化／生理作用

Cytidine 5′-diphosphocholine (CDP-choline) is an endogenous compound that plays an important role in the synthesis of phospholipids in the cell membrane. It acts as a choline donor for the biosynthesis of acetylcholine and phosphatidylcholine, a neuronal membrane phospholipid. CDP-choline enhances brain metabolism and influences the levels of various neurotransmitters including dopamine, epinephrine, and acetylcholine. It has been studied as a neuroprotectant after cerebral ischemia. CDP-choline is observed to exhibit therapeutic effects against cognitive impairment arising from multiple causes, cerebral vascular diseases, after-head trauma, and Alzheimer′s disease.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)