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Key Documents

208R-1

Sigma-Aldrich

GH (EP267) Rabbit Monoclonal Primary Antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

100
500

共軛

unconjugated

抗體表格

culture supernatant

抗體產品種類

primary antibodies

無性繁殖

EP267, monoclonal

描述

(For In Vitro Diagnostic Use in Select Regions (See Chart))

形狀

buffered aqueous solution

物種活性

human

包裝

bottle of 1.0 mL predilute (208R-17)
bottle of 7.0 mL predilute (208R-18)
vial of 0.1 mL concentrate (208R-14)
vial of 0.5 mL concentrate (208R-15)
vial of 1.0 mL concentrate (208R-16)

製造商/商標名

Cell Marque

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同型

IgG

運輸包裝

wet ice

儲存溫度

2-8°C

基因資訊

mouse ... Gh(14599)

一般說明

Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Human growth hormone contains 191 amino acid residues with two disulfide bridges. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).1-3 It reacts with GH-producing cells. Growth hormone receptors have been found in various non-pituitary cells, including that from hepatocellular carcinoma and various benign and malignant cutaneous lesions.4-6

品質


IVD

IVD

IVD

RUO

聯結

GH Positive Control Slides, Product No. 208S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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A Matsuno et al.
Pathology, research and practice, 197(1), 13-20 (2001-02-24)
To characterize the morphological and functional aspects of silent somatotroph adenomas with paradoxical responses of GH in TRH or GnRH provocation tests, which are considered to be a useful strategy for endocrinological identification of silent somatotroph adenomas, we examined three
L K Chopin et al.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 12(2), 126-136 (2002-08-15)
Prostate cancer is a significant cause of morbidity and mortality in Western males. While it is known that androgens play a central role in prostate cancer development and progression, other hormones and growth factors are also involved in prostate growth.
T García-Caballero et al.
Endocrine, 12(3), 265-271 (2000-08-30)
The liver is an essential target tissue for growth hormone (GH) and prolactin (PRL). The aim of this study was to determine the in situ expression of growth hormone receptor (GHR) and prolactin receptor (PRLR) in hepatocellular carcinomas and to
K S G Cunha et al.
Journal of clinical pathology, 56(10), 758-763 (2003-09-30)
The hallmark of neurofibromatosis type 1 (NF1) is the development of multiple neurofibromas. Solitary neurofibroma may occur in an individual who does not have NF1, but multiple neurofibromas tend to develop only in those with NF1. It has been suggested

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