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Key Documents

17248

Sigma-Aldrich

N-癸酰- DL -高丝氨酸内酯

≥97.0% (HPLC)

同義詞:

N-(tetrahydro-2-oxo-3-furanyl)-Decanamide

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About This Item

經驗公式(希爾表示法):
C14H25NO3
CAS號碼:
分子量::
255.35
Beilstein:
1644700
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.26

product name

N-癸酰- DL -高丝氨酸内酯, ≥97.0% (HPLC)

化驗

≥97.0% (HPLC)

形狀

powder

顏色

white

mp

111-114 °C

應用

cell analysis

儲存溫度

2-8°C

SMILES 字串

CCCCCCCCCC(=O)NC1CCOC1=O

InChI

1S/C14H25NO3/c1-2-3-4-5-6-7-8-9-13(16)15-12-10-11-18-14(12)17/h12H,2-11H2,1H3,(H,15,16)

InChI 密鑰

TZWZKDULKILUPV-UHFFFAOYSA-N

應用

应用试验:在通常不能产生高丝氨酸内酯的紫色色杆菌突变体中诱导紫色素表达。

生化/生理作用

N-癸酰基-DL-高丝氨酸内酯是N-酰基-高丝氨酸内酯家族的成员。N-酰基高丝氨酸内酯(AHL)调节革兰氏阴性菌中的基因表达,例如埃希氏杆菌沙门氏菌涉及细菌间的群体感应、细胞间通讯。一些AHL是人类免疫细胞(如嗜中性粒细胞)的强效化学诱导剂。
N-癸酰基-DL-高丝氨酸内酯(N-C10-HSL)属于一组高丝氨酸内酯,包括: N-辛酰基高丝氨酸内酯(N-C8-HSL)、N-(3-氧代十二烷酰基)高丝氨酸-L-内酯(3-oxo-C10 HSL),N-(3-氧代十二烷酰基)高丝氨酸-L-内酯(3- oxo-C12-HSL),N-(3-氧十二酰)-L-高丝氨酸内酯(3-oxo-C14-HSL、N-(3-羟基癸酰基)-L-高丝氨酸内酯和N-(3-羟基辛酰基)- L-高丝氨酸内酯参与细菌群体感应的过程,这些N-酰基高丝氨酸内酯用于研究细菌群体感应的过程和机制。

包裝

无底玻璃瓶。内含物装在插入的融合锥内。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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Ali Tahrioui et al.
Life (Basel, Switzerland), 3(1), 260-275 (2013-01-01)
Cell-to-cell communication, or quorum-sensing (QS), systems are employed by bacteria for promoting collective behaviour within a population. An analysis to detect QS signal molecules in 43 species of the Halomonadaceae family revealed that they produced N-acyl homoserine lactones (AHLs), which
Catarina A Santos et al.
Frontiers in microbiology, 11, 990-990 (2020-06-13)
The emergence of bacterial strains resistant to different antibiotics has prompted the search for new sources of antimicrobial compounds. Studies have shown that jambolan [Syzygium cumini (L.) Skeels], a tropical fruit from the Mirtaceae family, contains a great variety of
Tingting Li et al.
Journal of food science and technology, 55(8), 3016-3025 (2018-08-02)
The spoilage of aquatic products is mainly caused by the bacterial growth, and the specific spoilage organism (SSO) plays an important role. Quorum sensing (QS) is a microbial cell-cell communication system which is coordinated with the population density, and is
A A Purohit et al.
Journal of applied microbiology, 115(3), 835-847 (2013-06-04)
The aim of this study was to use a sensitive method to screen and quantify 57 Vibrionaceae strains for the production of acyl-homoserine lactones (AHLs) and map the resulting AHL profiles onto a host phylogeny. We used a high-performance liquid
Ping Kong et al.
BMC microbiology, 10, 313-313 (2010-12-09)
Oomycetes attack a huge variety of economically and ecologically important plants. These pathogens release, detect and respond to signal molecules to coordinate their communal behaviors including the infection process. When signal molecules are present at or above threshold level, single

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