61698
N-(3-Hydroxyoctanoyl)-DL-homoserine lactone
≥95% (sum of isomers, HPLC)
同義詞:
3-Hydroxy-N-(tetrahydro-2-oxo-3-furanyl)octanamide, 3-Hydroxy-C8-HSL, N-[(RS)-3-Hydroxyoctanoyl]-DL-homoserine lactone
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About This Item
經驗公式（希爾表示法）:
C12H21NO4
CAS號碼:
分子量：:
243.30
MDL號碼:
分類程式碼代碼:
41116134
PubChem物質ID:
NACRES:
NA.25
推薦產品
品質等級
化驗
≥95% (sum of isomers, HPLC)
儲存溫度
−20°C
SMILES 字串
O=C(CC(O)CCCCC)NC1C(OCC1)=O
InChI
1S/C12H21NO4/c1-2-3-4-5-9(14)8-11(15)13-10-6-7-17-12(10)16/h9-10,14H,2-8H2,1H3,(H,13,15)
InChI 密鑰
XCZVBYOXRSFQBH-UHFFFAOYSA-N
生化／生理作用
N-(3-Hydroxyoctanoyl)-DL-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria; for reviews see. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs, and a research focus for the prevention of biofilm formation.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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Bacteria use small molecule signals to access their local population densities in a process called quorum sensing (QS). Once a threshold signal concentration is reached, and therefore a certain number of bacteria have assembled, bacteria use QS to change gene
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C Fuqua et al.
Annual review of genetics, 35, 439-468 (2001-11-09)
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Streptococcus mutans is the primary causative agent involved in dental caries in humans. Among important virulence factors of this pathogen, its ability to form and sustain a polysaccharide-encased biofilm (commonly called dental plaque) is vital not only to its survival
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