135R-1

CD35 (EP197) Rabbit Monoclonal Primary Antibody

• 同義詞: C3-binding protein, C3BR, C3b/C4b receptor, C4BR, CD35 antigen, CR1, Complement Receptor 1, Complement component (3b/4b) receptor 1 (Knops blood group), Knops blood group antigen
• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100; 500
• 共軛: unconjugated
• 抗體表格: culture supernatant
• 抗體產品種類: primary antibodies
• 無性繁殖: EP197, monoclonal
• 描述: For In Vitro Diagnostic Use in Select Regions (See Chart)
• 形狀: buffered aqueous solution
• 物種活性: human
• 包裝: vial of 0.1 mL concentrate (135R-14); vial of 0.1 mL concentrate Research Use Only (135R-14-RUO); vial of 0.5 mL concentrate (135R-15); vial of 1.0 mL concentrate (135R-16); vial of 1.0 mL concentrate Research Use Only (135R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (135R-17-RUO); vial of 1.0 mL predilute ready-to-use (135R-17); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (135R-18-RUO); vial of 7.0 mL predilute ready-to-use (135R-18)
• 製造商／商標名: Cell Marque^™
• 濃度: 0.1-5.0 μg/mL (predilute); 2.5-125 μg/mL (concentrate)
• 技術: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• 同型: IgG
• 控制: tonsil
• 運輸包裝: wet ice
• 儲存溫度: 2-8°C
• 視覺化: membranous
• 基因資訊: human ... CR1(1378)

描述

一般說明

CD35 (complement receptor 1) is a cell membrane-bound, monomeric glycoprotein found on numerous cell types including erythrocytes, leukocytes, glomerular podocytes, and follicular dendritic cells. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. CD35 antigen is found on erythrocytes, B cells, a subset of T cells, monocytes, as well as eosinophils and neutrophils. Anti-CD35 is considered a mature B-cell marker which labels follicular dendritic reticulum cells and tumors derived from such cells such as follicular dendritic cell tumor/sarcoma.

品質

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

聯結

CD35 Positive Control Slides, Product No. 135S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

準備報告

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其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable