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Merck
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Key Documents

08520

Sigma-Aldrich

Quin-2

suitable for fluorescence, ≥95% (HPLC)

同義詞:

2-[(2-Amino-5-methylphenoxy)methyl]-6-methoxy-8-aminoquinoline-N,N,N′,N′-tetraacetic acid tetrapotassium salt, 2-{[2-Bis-(carboxymethyl)amino-5-methylphenoxy]-methyl}-6-methoxy-8-bis-(carboxymethyl)aminoquinoline tetrapotassium salt, Glycine,N-[2-[[8-[bis(carboxymethyl)amino]-6-methoxy-2-quinolinyl]methoxy]-4-methylphenyl]-N-(carboxymethyl)-,potassium salt (1:4), Quin 2, Tetrapotassium Salt, tetrapotassium 2-[[2-[[2-[bis(2-oxido-2-oxoethyl)amino]-5-methylphenoxy]methyl]-6-methoxyquinolin-8-yl]-(2-oxido-2-oxoethyl)amino]acetate

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About This Item

經驗公式(希爾表示法):
C26H23K4N3O10
CAS號碼:
分子量::
693.87
Beilstein:
5374262
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.32

化驗

≥95% (HPLC)

溶解度

H2O: 10 mg/mL

螢光

λex 332 nm; λem 493 nm in 0.1 M Tris pH 8.0, 10 mM Ca2+

適合性

suitable for fluorescence

儲存溫度

2-8°C

SMILES 字串

[K+].[K+].[K+].[K+].COc1cc(N(CC([O-])=O)CC([O-])=O)c2nc(COc3cc(C)ccc3N(CC([O-])=O)CC([O-])=O)ccc2c1

InChI

1S/C26H27N3O10.4K/c1-15-3-6-19(28(10-22(30)31)11-23(32)33)21(7-15)39-14-17-5-4-16-8-18(38-2)9-20(26(16)27-17)29(12-24(34)35)13-25(36)37;;;;/h3-9H,10-14H2,1-2H3,(H,30,31)(H,32,33)(H,34,35)(H,36,37);;;;/q;4*+1/p-4

InChI 密鑰

XAGUNWDMROKIFJ-UHFFFAOYSA-J

應用

Quin-2 has been demonstrated to be an indicator of Zn2+-protein complexes .

其他說明

A fluorescent highly selective Ca++ indicator exhibiting fast uptake and release of Ca++; Calibration substance in the measurement of cytoplasmic free calcium

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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A new family of high-affinity buffers and optical indicators for Ca2+ is rationally designed and synthesized. The parent compound is 1,2-bis(o-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA), a relative of the well-known chelator EGTA [ethylene glycol bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid] in which methylene links between
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The Journal of cell biology, 94(2), 325-334 (1982-08-01)
A new, fluorescent, highly selective Ca2+ indicator , "quin2", has been trapped inside intact mouse and pig lymphocytes, to measure and manipulate cytoplasmic free Ca2+ concentrations, [Ca2+]i. Quin2 is a tetracarboxylic acid which binds Ca2+ with 1:1 stoichiometry and an
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