Y0001901

氯胍 盐酸盐

European Pharmacopoeia (EP) Reference Standard

• 同義詞: Chlorguanide, N¹-(4-Chlorophenyl)-N⁵-isopropylbiguanide
• 經驗公式（希爾表示法）: C₁₁H₁₆ClN₅·HCl
• CAS號碼: 637-32-1
• 分子量：: 290.19
• EC號碼: 211-283-7
• MDL號碼: MFCD01732193
• 分類程式碼代碼: 41116107
• NACRES: NA.24

屬性

• 等級: pharmaceutical primary standard
• API 家族: proguanil
• 製造商／商標名: EDQM
• 格式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: Cl.CC(C)NC(=N)NC(=N)Nc1ccc(Cl)cc1
• InChI: 1S/C11H16ClN5.ClH/c1-7(2)15-10(13)17-11(14)16-9-5-3-8(12)4-6-9;/h3-7H,1-2H3,(H5,13,14,15,16,17);1H
• InChI 密鑰: SARMGXPVOFNNNG-UHFFFAOYSA-N

描述

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Proguanil hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

生化／生理作用

Chlorguanide (proguanil) is combined with atovaquone for malaria prophylaxis. The two compounds act synergistically to inhibit the plasmodial dihydrofolate reductase (DHFR) and interrupt the electron transport chain. Mutations in DHFR account for the development of resistant strains.

包裝

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他說明

Sales restrictions may apply.

安全資訊

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301
• 防範說明: P301 + P330 + P331 + P310
• 危險分類: Acute Tox. 3 Oral
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable