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Key Documents

PHR1752

Supelco

安非他酮相关化合物A

Pharmaceutical Secondary Standard; Certified Reference Material

同義詞:

2-(tert-Butylamino)-4′-chloropropiophenone hydrochloride, 2-(tert-butylamino)-3’-bromopiophenone hydrochloride

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About This Item

經驗公式(希爾表示法):
C13H18ClNO · HCl
CAS號碼:
分子量::
276.20
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to USP 1078744

API 家族

bupropion

CofA

current certificate can be downloaded

包裝

pkg of 30 mg

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

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一般說明

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Bupropion hydrochloride (BUP) and its derivatives belong to a chemical class of aminoketones and are known for their antidepressant abilities. BUP selectively inhibits the neuronal reabsorption of catecholamines (noradrenalin and dopamine), has minimal effect on the recapture of indolamines (serotonin) and no inhibitory effect on monoamine oxidase. It is used as the non-nicotine pharmacological therapy for combating smoking in controlled release form.
Bupropion hydrochloride (BUP) may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometric and chromatographic techniques.

應用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA7916 in the slot below. This is an example certificate only and may not be the lot that you receive.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

相關產品

產品號碼
描述
訂價

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Use of charge transfer complexation reaction for the spectrophotometric determination of bupropion in pharmaceuticals and spiked human urine.
Basavaiah K and Abdulrahman SAM
The Thai Journal of Pharmaceutical Sciences, 34(4), 257-261 (2010)
Spectroscopic investigations on the inclusion interaction between hydroxypropyl-β-cyclodextrin and bupropion
Misiuk W and Zalewska M
Journal of Molecular Liquids, 159(3), 220-225 (2011)
Titrimetric and spectrophotometric assay of bupropion hydrochloride in pharmaceuticals using mercury (II) nitrate
Abdulaziz MA, et al.
Ecletica Quimica, 35(3), 9-16 (2010)
Determination of bupropion using liquid chromatography with fluorescence detection in pharmaceutical preparations, human plasma and human urine
Ulu ST and Tuncel M
Journal of Chromatographic Science, 50(5), 433-439 (2012)
Structures from powders: Bupropion hydrochloride
Maccaroni E, et al
Journal of Pharmaceutical and Biomedical Analysis, 50(2), 257-261 (2009)

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