PHR1611

巯嘌呤

Pharmaceutical Secondary Standard; Certified Reference Material

• 同義詞: 6-巯基嘌呤 一水合物, 6-嘌呤硫醇, 6-硫代嘌呤
• 經驗公式（希爾表示法）: C₅H₄N₄S·H₂O
• CAS號碼: 6112-76-1
• 分子量：: 170.19
• Beilstein: 4012091
• EC號碼: 200-037-4
• MDL號碼: MFCD03854445
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823508
• NACRES: NA.24

屬性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to BP 773; traceable to USP 1392002
• API 家族: mercaptopurine
• CofA: current certificate can be downloaded
• 包裝: pkg of 1 g
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 應用: pharmaceutical (small molecule)
• 形式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: O.S=C1NC=Nc2nc[nH]c12
• InChI: 1S/C5H4N4S.H2O/c10-5-3-4(7-1-6-3)8-2-9-5;/h1-2H,(H2,6,7,8,9,10);1H2
• InChI 密鑰: WFFQYWAAEWLHJC-UHFFFAOYSA-N
• 基因資訊: human ... PPAT(5471)

描述

一般說明

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Mercaptopurine is an anticancer and an immunosuppressive drug employed for the management of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn′s disease, etc. Its mode of action involves interference in the nucleic acid synthesis by the inhibition of purine metabolism.

應用

Mercaptopurine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations, suspensions, and double drug liposomes by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAC3476 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全資訊

• 象形圖: GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H301,H341,H361fd
• 防範說明: P202 - P264 - P280 - P301 + P310 - P405 - P501
• 危險分類: Acute Tox. 3 Oral - Muta. 2 - Repr. 2
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3