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重要文件

PHR1590

Supelco

杆菌肽

Pharmaceutical Secondary Standard; Certified Reference Material

同義詞:

杆菌肽

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About This Item

經驗公式(希爾表示法):
C66H103N17O16S
CAS號碼:
分子量::
1422.69
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to USP 1048007

API 家族

bacitracin

CofA

current certificate can be downloaded

包裝

pkg of 1 g

技術

HPLC: suitable
gas chromatography (GC): suitable

mp

221-225 °C (lit.)

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

-10 to -25°C

SMILES 字串

CCC(C)C(N)C1=NC(CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC

InChI

1S/C66H103N17O16S/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88)/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-/m0/s1

InChI 密鑰

CLKOFPXJLQSYAH-RNHDWVCBSA-N

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一般說明

Bacitracin is a polypeptide antibiotic recovered from certain strains of B. subtilis and B. licheniformis. Its mode of action involves the inhibition of bacterial cell wall synthesis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Bacitracin may be used as a pharmaceutical secondary reference standard for the determination of the analyte in serum samples and food samples by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA4581 in the slot below. This is an example certificate only and may not be the lot that you receive.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


從最近期的版本中選擇一個:

分析證明 (COA)

Lot/Batch Number

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Bacitracin: a new antibiotic produced by a member of the B. subtilis group
Johnson BA, et al.
Science (New York, N.Y.), 102(2650), 376-377 (1945)
Analysis of major components of residual bacitracin and colistin in food samples by liquid chromatography tandem mass spectrometry
Sin DW, et al.
Analytica Chimica Acta, 535(1-2), 23-31 (2005)
Bacitracin: an inhibitor of the dephosphorylation of lipid pyrophosphate, an intermediate in the biosynthesis of the peptidoglycan of bacterial cell walls
Siewert G and Strominger JL
Proceedings of the National Academy of Sciences of the USA, 57(3), 767-767 (1967)
Determination of neomycin and bacitracin in human or rabbit serum by HPLC--MS/MS
Mascher DG, et al.
Journal of Pharmaceutical and Biomedical Analysis, 43(2), 691-700 (2007)

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