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重要文件

PHR1476

Supelco

邻苯二甲酸二乙酯

Pharmaceutical Secondary Standard; Certified Reference Material

同義詞:

邻苯二甲酸二乙酯, DEP

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About This Item

線性公式:
C6H4-1,2-(CO2C2H5)2
CAS號碼:
分子量::
222.24
Beilstein:
1912500
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to Ph. Eur. D1410000
traceable to USP 1193505

蒸汽密度

7.66 (vs air)

蒸汽壓力

1 mmHg ( 100 °C)

API 家族

diethyl phthalate

CofA

current certificate can be downloaded

自燃溫度

854 °F

expl. lim.

0.75 %, 187 °F

包裝

pkg of 1 g

技術

HPLC: suitable
gas chromatography (GC): suitable

折射率

n20/D 1.502 (lit.)

bp

298-299 °C (lit.)

mp

−3 °C (lit.)

密度

1.12 g/mL at 25 °C (lit.)

應用

pharmaceutical (small molecule)

形式

neat

儲存溫度

2-30°C

SMILES 字串

CCOC(=O)c1ccccc1C(=O)OCC

InChI

1S/C12H14O4/c1-3-15-11(13)9-7-5-6-8-10(9)12(14)16-4-2/h5-8H,3-4H2,1-2H3

InChI 密鑰

FLKPEMZONWLCSK-UHFFFAOYSA-N

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一般說明

Diethyl Phthalate is a phthalic acid ester, commonly synthesized by the condensation of the carboxy groups of phthalic acid with methanol.. It is used as a solvent for fragrance in cosmetic formulations and personal care products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

應用

Diethyl Phthalate may be used as a pharmaceutical reference standard for the determination of the analyte in cosmetic products, pharmaceutical formulations and dietary supplements by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA3024 in the slot below. This is an example certificate only and may not be the lot that you receive.

推薦產品

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

338.0 °F - closed cup

閃點(°C)

170 °C - closed cup


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分析證明 (COA)

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存取文件庫

Identification of phthalates in medications and dietary supplement formulations in the United States and Canada
Kelley K, et al.
Environmental Health Perspectives, 120(3), 379-384 (2011)
Phthalic Acid and Derivatives
Ullmann's Encyclopedia of Industrial Chemistry (2007)
Gas chromatography in routine pharmaceutical analysis
Baines CB and Proctor KA
The Journal of Pharmacy and Pharmacology, 11(S1), 230T-234T (1959)
Analysis of consumer cosmetic products for phthalate esters.
Hubinger JC and Havery DC
Journal of Cosmetic Science, 57(2), 127-137 (2006)
Simultaneous determination of seven phthalates and four parabens in cosmetic products using HPLC-DAD and GC-MS methods
Shen Y-H, et al.
Journal of Separation Science, 30(1), 48-54 (2007)

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