PHR1164

盐酸胺碘酮 盐酸盐

Pharmaceutical Secondary Standard; Certified Reference Material

• 同義詞: 2-丁基-3-苯并呋喃基-4-[2-（二乙氨基）乙氧基]-3,5-二碘苯基酮 盐酸盐, （2-丁基-3-苯并呋喃基） [4-[2-（二乙氨基）乙氧基]-3,5-二碘苯基] 甲酮 盐酸盐
• 經驗公式（希爾表示法）: C₂₅H₂₉I₂NO₃ · HCl
• CAS號碼: 19774-82-4
• 分子量：: 681.77
• EC號碼: 243-293-2
• MDL號碼: MFCD00069204
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329823181
• NACRES: NA.24

屬性

• 等級: certified reference material; pharmaceutical secondary standard
• 品質等級: 300
• agency: traceable to BP 532; traceable to Ph. Eur. A0575000; traceable to USP 1027302
• API 家族: amiodarone
• CofA: current certificate can be downloaded
• 技術: HPLC: suitable; gas chromatography (GC): suitable
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: C(=O)(C=1C=2C(OC1CCCC)=CC=CC2)C3=CC(I)=C(OCCN(CC)CC)C(I)=C3.Cl
• InChI: 1S/C25H29I2NO3.ClH/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3;/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3;1H
• InChI 密鑰: ITPDYQOUSLNIHG-UHFFFAOYSA-N

描述

一般說明

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Amiodarone hydrochloride is an antiarrhythmic drug used for the treatment of ventricular and supraventricular tachycardia.

應用

Amiodarone hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化／生理作用

Non-selective ion channel blocker. Amiodarone induces an immediate influx of Ca²⁺ in Saccharomyces cerevisiae, followed by mitochondrial fragmentation and cell death.

分析報告

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Values of analytes vary lot to lot.

腳註

To see an example of a Certificate of Analysis for this material enter LRAC3555 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全資訊

• 象形圖: GHS08,GHS07,GHS09
• 訊號詞: Warning
• 危險聲明: H315,H319,H335,H351,H361fd,H362,H410
• 防範說明: P260 - P263 - P273 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• 危險分類: Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Irrit. 2 - Lact. - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable